Skip to main content

Table 4 Association of CD36 haplotypes with lipid levels

From: CD36 haplotypes are associated with lipid profile in normal-weight subjects

Haplotype Cases (n = 96) LDL-C >100 mg/dL Controls (n = 134) OR (95% CI) P value
AGTIG (0.046) (0.035) 1.28 (0.50-3.28) 0.59
11111
AGTIC (0.088) (0.081) 1.06 (0.54-2.08) 0.84
11112
AATIC (0.365) (0.340) 1.08 (0.73-1.61) 0.68
12112
AATDC (0.060) (0.019) 3.25 (1.12-9.40) 0.02
12122
AACID (0.116) (0.145) 0.75 (0.42-1.31) 0.31
12212
GGTIG (0.045) (0.099) 0.42 (0.19-0.92) 0.02
21111
GGTIC (0.042) (0.034) 1.21 (0.46-3.20) 0.69
21112
GGCIG (0.050) (0.086) 0.55 (0.25-1.19) 0.12
21211
GGCIC (0.112) (0.066) 1.74 (0.90-3.37) 0.09
21212     
Haplotype Cases (n = 26) Cholesterol total >200 mg/dL Controls (n = 206) OR (95% CI) P value
AGTIC (0.052) (0.087) 0.60 (0.16-2.15) 0.43
11112
AGCIC (0.031) (0.012) 2.86 (0.46-17.50) 0.23
11212
AATIC (0.472) (0.332) 2.02 (1.09-3.74) 0.02
12112
AATDC (0.020) (0.044) 0.46 (0.06-3.43) 0.44
12122
AACIC (0.109) (0.131) 0.85 (0.33-2.13) 0.72
12212
GGTIG (0.021) (0.081) 0.25 (0.037-1.74) 0.13
21111
GGTIC (0.022) (0.039) 0.58 (0.086-3.95) 0.57
21112
GGCIG (0.083) (0.068) 1.30 (0.45-3.77) 0.62
21211
GGCIC (0.080) (0.088) 0.94 (0.32-2.74) 0.92
21212     
  1. 1 = Major allele, 2 = minor allele. Markers: -33137A/G, -31118G/A, -22674 T/C, 27645Ins/Del, 30294G/C polymorphisms of CD36 gene.