Cheek cell fatty acids reflect n-3 PUFA in blood fractions during linseed oil supplementation: a controlled human intervention study

Grindel, Annemarie; Staps, Frank; Kuhnt, Katrin

doi:10.1186/1476-511X-12-173

Lipids in Health and Disease

Table 5 Correlation between cheek cell FA with FA of plasma, RBC and PBMC

From: Cheek cell fatty acids reflect n-3 PUFA in blood fractions during linseed oil supplementation: a controlled human intervention study

	Baseline					Intervention^‡
	Total subjects					Test group – linseed oil mix			Control group – olive oil
	(n = 38)					(n = 46)			(n = 30)
	Cheek cell correlation			Plasma correlation		Cheek cell correlation			Cheek cell correlation
	Plasma	RBC	PBMC	RBC	PBMC	Plasma	RBC	PBMC	Plasma	RBC	PBMC
	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹	r ¹
SFA
C16:0	-0.08	-0.1	0.09	0.80**	0.31	-0.01	-0.2	-0.1	0.34	-0.17	0.34
C18:0	0.04	-0.16	-0.07	0.60**	0.15	0.09	0.04	-0.14	0.05	0.22	-0.03
n-9 MUFA
C18:1n-9 (OA)	0.34*	0.06	0.19	0.16	0.26	0.11	-0.05	-0.01	0.43*	0.25	0.2
Total n-9	0.33*	0.08	0.16	0.17	0.23	0.11	-0.05	0	0.43*	0.29	0.25
n-6 PUFA
C18:2n-6 (LA)	-0.59	0.21	0.31	0.58**	-0.13	-0.01	0.11	0.12	0.34	0.65**	0.73**
C18:3n-6	0.33*	0.44**	0.1	0.72**	0.07	0.16	0.35*	0.14	0	0.24	0.40*
C20:3n-6	0.41**	0.47**	0.44**	0.86**	0.70**	0.44**	0.50**	0.39**	0.56**	0.65**	0.64**
C20:4n-6 (AA)	0.54**	0.54**	-0.21	0.54**	0.09	0.41**	0.41**	-0.15	0.38*	0.50**	0.12
C22:5n- 6	0.52**	0.58**	0.60**	0.79**	0.76**	0.22	0.27	0.2	0.52**	0.68**	0.54**
Total n-6	-0.22	-0.07	-0.11	0.22	-0.04	-0.19	-0.25	-0.05	0.23	0.44*	0.22
n-3 PUFA
C18:3n-3 (ALA)	0.17	0.06	0.07	0.70**	0.43**	0.33*	0.43**	0.22	0.31	0.1	-0.17
C20:4n-3 (ETA)	0.54**	0.59**	0.48**	0.92**	0.80**	0.36**	0.58**	0.48**	0.60**	0.59**	0.70**
C20:5n-3 (EPA)	0.81**	0.82**	0.62**	0.84**	0.72**	0.69**	0.72**	0.54**	0.84**	0.83**	0.83**
C22:5n-3 (DPA)	0.73**	0.67**	0.47**	0.83**	0.74**	0.55**	0.41**	0.49**	0.48**	0.51**	0.37*
C22:6n-3 (DHA)	0.68**	0.64**	0.59**	0.88**	0.80**	0.50**	0.59**	0.56**	0.61**	0.59**	0.64**
Total n-3	0.58**	0.61**	0.50**	0.85**	0.66**	0.45**	0.57**	0.55**	0.58**	0.64**	0.60**
Sum
Σ SFA	-0.24	-0.25	0.05	0.52	-0.25	-0.05	-0.24	0.01	0.27	0.01	0.09
Σ MUFA	0.27	0.06	-0.06	0.12	0.14	0.00	0.05	-0.09	0.32	0.24	0.06
Σ PUFA	-0.21	-0.07	-0.2	0.23	-0.10	-0.16	-0.12	-0.01	0.17	0.09	0.11

^‡Results of day 7 and day 56 of each intervention combined.
¹r Pearson's correlation coefficient; * P ≤ 0.05, ** P ≤ 0.01.

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ISSN: 1476-511X

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