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Table 2 Fatty acid composition and FA enzyme indices in the three different groups of rats

From: Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

SAT-TG

 

OP

 

OR

 

HFD-paired

 
 

Mean

SD

Mean

SD

Mean

SD

SCD-16

0.15#, ††

0.03

0.11

0.04

0.12

0.02

SCD-18

7.6##

0.7

7.0

0.7

6.5

0.6

D6D a

2.1 *10-3

0.6 *10-3

2.3 *10-3

0.9 *10-3

2.4 *10-3

1.3 *10-3

D5D

6.5

1.2

6.3

1.3

5.7

1.3

DNL

0.94

0.06

0.89

0.06

0.88

0.05

EI

0.22##

0.02

0.24

0.04

0.27

0.03

16:1n-7

3.43#, ††

0.67

2.49

0.83

2.63

0.44

18:2n-6

24.76#, ††

1.07

25.94

0.67

25.69

0.83

18:3n-3 a

1.47##

0.07

1.47‡‡

0.12

1.35

0.05

20:5n-3

0.03

0.01

0.03

0.01

0.02

0.00

22:6n-3

0.10#

0.03

0.09

0.02

0.07

0.02

PL-CE

 

OP

 

OR

 

HFD-paired

 
 

Mean

SD

Mean

SD

Mean

SD

SCD-16

0.11

0.02

0.09

0.02

0.10

0.03

SCD-18

7.7

1.2

7.9

1.5

7.8

1.8

D6D

15 *10-3

2 *10-3

14 *10-3

3 *10-3

16 *10-3

4 *10-3

D5D

271

23

277

27

248

55

DNL a

0.43

0.06

0.40

0.03

0.40

0.05

EI

0.13

0.02

0.13

0.03

0.16

0.03

16:1n-7

0.75

0.12

0.65

0.12

0.74

0.22

18:2n-6 a

16.77

1.43

17.80

1.67

18.04

2.76

18:3n-3

0.13#

0.03

0.13

0.03

0.17

0.04

20:5n-3

0.16

0.02

0.13

0.03

0.18

0.04

22:6n-3

1.37

0.14

1.47

0.21

1.27

0.20

PL-PL

 

OP

 

OR

 

HFD-paired

 
 

Mean

SD

Mean

SD

Mean

SD

SCD-16

0.012

0.002

0.011

0.003

0.011

0.003

SCD-18

0.19

0.03

0.21

0.03

0.22

0.03

D6D b

3.4 *10-3

0.8 *10-3

3.2 *10-3

0.4 *10-3

N/A

N/A

D5D

43

6

45

5

39

9

DNL

0.92

0.13

0.90

0.07

0.95

0.24

EI a

1.85###

0.19

1.74‡‡

0.24

1.53

0.061

16:1n-7

0.18

0.03

0.18

0.04

0.20

0.05

18:2n-6

17.76

2.95

18.50

1.80

20.06

3.33

18:3n-3 a

0.08

0.02

0.06

0.02

0.09

0.03

20:5n-3 a

0.08

0.01

0.09

0.01

0.10

0.02

22:6n-3

4.22#

0.46

4.18

0.74

3.48

0.62

Liver PL

 

OP

 

OR

 

HFD-paired

 
 

Mean

SD

Mean

SD

Mean

SD

SCD-16

0.013

0.004

0.011

0.003

0.011

0.004

SCD-18 a

0.16

0.02

0.16

0.03

0.16

0.03

D6D a

12 *10-3

1 *10-3

11 *10-3

2 *10-3

12 *10-3

2 *10-3

D5D a

58

7

61

6

58

17

DNL

2.0

0.1

2.0

0.2

2.0

0.4

EI

1.9

0.1

1.9

0.2

1.7

0.1

16:1n-7

0.18

0.03

0.18

0.04

0.20

0.05

18:2n-6

7.90

0.78

7.85

1.02

8.93

1.61

20:5n-3

0.07

0.01

0.07

0.01

0.08

0.02

22:6n-3

7.84

0.96

8.51‡‡

1.23

7.08

0.79

Liver TG

 

OP

OR

HFD-paired

 

Mean

SD

Mean

SD

Mean

SD

SCD-16 a

0.047

0.020

0.040

0.008

0.039

0.013

SCD-18

14

1

13

1

13

1

D6D

15 *10-3

2 *10-3

15 *10-3

2 *10-3

15 *10-3

2 *10-3

D5D

6.8

0.5

6.9

0.7

6.8

1.0

DNL a

1.1

0.3

1.0

0.1

1.0

0.1

EI a

0.10

0.00

0.11

0.01

0.10

0.01

16:1n-7 a

1.28

0.66

1.01

0.22

1.03

0.36

18:2n-6 a

25.12

2.99

25.90

1.67

26.39

2.05

18:3n-3

0.85

0.15

0.83

0.11

0.85

0.12

20:5n-3

0.18

0.06

0.17

0.04

0.17

0.03

22:6n-3 a

1.15

0.43

1.16

0.42

1.02

0.35

  1. Fatty acid (FA) composition and FA enzyme indices in five lipid fractions in obesity-prone (OP) and obesity-resistant (OR) rats with ad libitum HFD access (AL-HFD), and energy-restricted HFD-paired rats (HFD-paired). FAs are presented as relative percentages of total FAs within each lipid fraction. The symbol # indicates a significant difference between OP and HFD-paired; between OP and OR; between OR and HFD-paired. Level of significance: #//, P < 0.05; ##/††/‡‡, P < 0.01; ###/†††/‡‡‡, P < 0.001. N/A, not available. All tests were done using One-Way ANOVAs, followed by Tukey’s t-test when significant; or Kruskal Wallis test (for non-normally distributed data; indicated by a superscript “;a” where performed), followed by Dunn’s multiple comparison test when significant. Where data for only two groups was available, Student’s t-test was used (indicated by a superscript “;b” where performed) for normally distributed data.