Table 3 The combined effects of SIRT1 haplotype and n-6/n-3 PUFA intake ratio on serum LDL-C and HDL-C levels
Male | Female | |||||||
|---|---|---|---|---|---|---|---|---|
Low n6/n3 intake group(<3.79) | High n6/n3 intake group(≧3.79) | Low n6/n3 intake group(<3.93) | High n6/n3 intake group(≧3.93) | |||||
n | (mg/dl) | n | (mg/dl) | n | (mg/dl) | n | (mg/dl) | |
LDL-Cholesterol | ||||||||
Haplotype 1 (+) | 221 | 133.5 ± 31.1 | 232 | 131.1 ± 29.3 | 215 | 133.6 ± 30.5 | 213 | 131.2 ± 31.3 |
Haplotype 1 (−) | 88 | 127.0 ± 29.8 | 74 | 129.4 ± 28.6 | 93 | 131.3 ± 26.2 | 84 | 131.1 ± 28.1 |
P-value | 0.13 | 0.68 | 0.53 | 0.87 | ||||
Haplotype 2 (+) | 179 | 128.0 ± 30.5 | 149 | 129.4 ± 28.6 | 187 | 129.7 ± 27.6 | 163 | 130.2 ± 30.6 |
Haplotype 2 (−) | 130 | 136.6 ± 30.7 | 157 | 131.9 ± 29.7 | 121 | 137.9 ± 31.0 | 134 | 132.4 ± 30.1 |
P-value | 0.0089 | 0.28 | 0.0085 | 0.68 | ||||
Haplotype 3 (+) | 82 | 136.8 ± 30.2 | 95 | 131.5 ± 31.6 | 82 | 131.1 ± 25.1 | 98 | 134.0 ± 30.2 |
Haplotype 3 (−) | 227 | 129.8 ± 30.9 | 211 | 130.3 ± 28.1 | 226 | 133.6 ± 30.6 | 199 | 129.8 ± 30.5 |
P-value | 0.033 | 0.56 | 0.99 | 0.49 | ||||
HDL-Cholesterol | ||||||||
Haplotype 1 (+) | 223 | 55.7 ± 16.8 | 234 | 56.8 ± 15.9 | 218 | 72.1 ± 17.2 | 220 | 69.0 ± 16.7 |
Haplotype 1 (−) | 89 | 58.3 ± 16.7 | 77 | 57.0 ± 16.0 | 96 | 76.9 ± 17.8 | 91 | 69.5 ± 17.4 |
P-value | 0.16 | 0.72 | 0.022 | 0.92 | ||||
Haplotype 2 (+) | 181 | 57.6 ± 17.1 | 152 | 57.4 ± 16.4 | 190 | 75.5 ± 17.4 | 170 | 69.4 ± 17.1 |
Haplotype 2 (−) | 131 | 54.8 ± 16.4 | 159 | 56.4 ± 15.4 | 124 | 70.5 ± 17.4 | 141 | 68.9 ± 16.7 |
P-value | 0.079 | 0.27 | 0.032 | 0.83 | ||||
Haplotype 3 (+) | 84 | 53.8 ± 14.9 | 97 | 56.6 ± 15.0 | 84 | 71.3 ± 17.1 | 104 | 69.6 ± 17.7 |
Haplotype 3 (−) | 228 | 57.4 ± 17.4 | 214 | 57.0 ± 16.3 | 230 | 74.4 ± 17.6 | 207 | 68.9 ± 16.5 |
P-value | 0.14 | 0.90 | 0.15 | 0.72 | ||||