Figure 3

Effect of WP supplementation on pro-inflammatory cytokines in the wound tissue of diabetic mice. The levels of IL-6 (A), TGF-β (B) and TNF-α (C) in the excisional wound tissue collected from the three groups of mice on days 1, 4, 7, 10 and 13 post wounding were measured using ELISAs. The cytokines levels from the control skin (day 0, an hour before wounding) were also measured in the three groups of mice. The data were first tested for normality and variance homogeneity prior to any further statistical analysis. The data were normally distributed, are presented as the amount of cytokines (pg) per mg of tissue and are expressed as the mean ± SEM. ^*P < 0.05, diabetic vs. control; ⁺P < 0.05, diabetic + WP vs. control; ^#P < 0.05, diabetic + WP vs. diabetic (ANOVA with Tukey’s post-test).