Effects of hyperlipidemia on protein expressions of α-SMA and E-cadherin (A) Immunohistochemical staining of α-SMA and E-cadherin in kidneys. Increased expression of α-SMA and decreased expression E-cadherin were observed in the tubular interstitium of the HF group when compared with the control group. (B) Western blot analysis for the protein expressions of α-SMA and E-cadherin in kidneys. (C) The histogram represents mean ± SD of the densitometric scans for the protein bands of α-SMA and E-cadherin from eight experiments, normalized by comparison with β-actin. * P < 0.05 vs. control.