Table 3 SNP included in analyses
Name | Gene, function | Chromosome | dbSNP identifier | n |
|---|---|---|---|---|
Apolipoprotein A1 | APOA1, protein component of HDL, promotes cholesterol efflux from tissues to liver | 11 | rs2727784 | 1 |
Apolipoprotein A5 | APOA5, protein component of HDL, regulates plasma triglycerides | 11 | rs3135506, rs662799, rs12272004 | 3 |
ATP-binding cassette, subfamily A, member 1 | ABCA1, transport AAs, sugars, vitamins, cholesterol, pt-choline to lipid acceptor apoA1 | 9 | rs2230806, rs2230808, rs4149267, rs4149327 | 4 |
β-Carotene 15,15’-monooxygenase 1 | BCMO1, cleave β-carotene | 16 | rs12934922, rs6564851, rs7501331 | 3 |
β-Carotene oxygenase 2 | BCMO2, cleave β-carotene | 11 | rs11214139, rs2250417, rs35361223 | 3 |
Betaine-homocysteine S-methyl transferase | BHMT, methylate Hcy | 5 | rs3733890 | 1 |
Cholesteryl ester transfer protein, plasma | CETP, transfer cholesterol | 16 | rs12708980, rs5880, rs5882, rs7205804, rs7499892 | 5 |
Cystathionine β-synthase | CBS, synthesize cystathionine | 21 | rs5742905 | 1 |
Cytochrome P450, family 4, subfamily F, polypeptide 2 | CYP4F2, involved in cholesterol synthesis | 19 | rs3093156, rs2108622, rs3093168, rs3093194 | 4 |
Folate hydrolate (prostate specific membrane antigen) 1 | FOLH1 (GCPII), hydrolyze folate | 11 | rs61886492 | 1 |
Methionine synthase reductase | MTRR, remethylate Hcy | 5 | rs1801394 | 1 |
Methylenetetrahydro-folate reductase | MTHFR, distribute one carbon units | 1 | rs1801131, rs1801133 | 2 |
5-Methyltetra-hydrofolate-homocysteine methyltransferase | MTR, remethylate Hcy | 1 | rs1805087 | 1 |
Microsomal triglyceride transfer protein | MTTP, lipoprotein assembly | 4 | rs10516445, rs1057613, rs3828542, rs881980 | 4 |
Niemann-Pick disease, type C1, gene-like 1 | NPC1L1, absorption of intestinal cholesterol and α-tocopherol transport | 7 | rs11763759, rs217420, rs217430, rs217432 | 4 |
Retinol binding protein 1, cellular | CRBP2 (RBP2), | 3 | rs2118981, rs35674260, rs3772875 | 3 |
Scavenger receptor class B, member 1 | SCARB1, intestinal absorption of carotenoids | 12 | rs10773105, rs12582221, rs7306660, rs7967521, rs838892 | 5 |
Serine palmitoyltransferase, long chain base subunit 1 | SPTLC1, sphingolipid biosynthesis | 9 | rs11790991, rs2297568, rs7858659 | 3 |
Solute carrier family 19 (folate transporter), member 1 | SLC19A1, reduced folate carrier | 21 | rs13050920, rs3788205, rs3788199 | 3 |
Solute carrier family 46 (folate transporter), member 1 | SLC46A1, proton coupled folate transporter (PCFT) | 17 | rs11080058, rs1128162, rs17719944, rs35714695, rs739439 | 5 |
CD36 Thrombospondin receptor | CD36, platelet surface glycoprotein, binds to oxidized LDL | 7 | rs1358337, rs3211834, rs3211931, rs3211956 | 4 |
α-Tocopherol transfer protein | α-TTP, transport α-tocopherol | 8 | rs4501570, rs4587328, rs4606052 | 3 |
Transcobalamin II | TCII, transport vitamin B12 | 22 | rs1801198 | 1 |
Total SNP included in analysis | 65 | |||