Figure 7

Transcriptomic analysis of colon preparation in healthy and colitic mice. Shown is Venn diagram made with significantly regulated colonic genes (P < 0.001) showing the relative impact of diet (treatment) vs. colitis (induction) and interaction between diet and colitis (A). Two-dimensional visualization of unsupervised PCA analysis constructed with the whole set of gene significantly differentially expressed in the colon upon colitis induction (B). Each dot represents the value obtained with an individual mouse (n = 6-9 mice per group). Of note top 40 colonic genes up- and down regulated in colitis mice and corresponding value are given in Additional files 3 and 4.