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Table 3 Average body and liver weights of rats during 30 days of treatment with ME and VO fractions

From: Elucidation of mechanisms of actions of thymoquinone-enriched methanolic and volatile oil extracts from Nigella sativa against cardiovascular risk parameters in experimental hyperlipidemia

Group Body weight per rat (g) Liver weight per rat (g)
  Prior to treatment Post treatment  
NLP-C 233.30 ± 20.8 278.60 ± 16.72 5.44 ± 0.22
HLP-C 22.00 ± 14.71 334.50 ± 14.50 (+20.06%)α 6.51 ± 0.01 (+19.65%)α
HLP- ME 221.25 ± 13.14 240.25 ± 9.74 (-28.18%)b 5.48 ± 0.03 (-15.82%)b
HLP-VO 220.00 ± 10.80 250.75 ± 4.85 (-25.04%)b 5.43 ± 0.07 (-16.59%)b
  1. Each value is mean ± SD from 4 rats in each group except NLP (n = 5). NLP-C, normolipidemic control fed 1 ml saline/rat/day; HLP-C, hyperlipidemic control given 1 ml of saline before the feeding of 1 ml suspension containing 5 mg cholesterol, 30 mg coconut oil and 2.5 mg cholic acid /rat/day; whereas rats in HLP-ME, HLP-VO were fed 1 ml of 100 mg ME, 20 mg VO prior to administration of 1 ml of the above atherogenic suspension /rat/day for 30 days. Note: All the values in NLP-C and HLP-C control groups in this manuscript were already presented in our previously published article [37]. The values were statistically significant from NLP-C at ap < 0.05 and HLP-C at bp < 0.05.