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Table 2 Comparison of metabolic and vascular characteristics between control subjects and GDM subjects

From: Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results

 

Control subjects

GDM

p-value

Fasting glucose (mmol/l)

5.03 ± 0.46

5.42 ± 1.64*

0.01

Fasting insulinemia (μUI/ml)

10.59 ± 11.1

13.19 ± 10.05

0.67

Triglyceride (mmol/l)

1.99 ± 0.23

2.4 ± 0.93

0.38

Total cholesterol (mmol/l)

5.12 ± 1.26

5.43 ± 1.54**

<0.0001

HDL cholesterol (mmol/l)

1.47 ± 0.55

1.31 ± 0.3*

0.018

LDL cholesterol (mmol/l)

2.59 ± 1.39

2.94 ± 1.27

0.47

Apo A1 (g/l)

1.90 ± 0.7

1.50 ± 0.34**

0.001

Apo B (g/l)

1.36 ± 0.5

1.22 ± 0.43

0.64

Urea (mmol/l)

3.83 ± 1.16

2.44 ± 0.89*

0.050

Creatinine (μmol/l)

49.99 ± 0.15

50.74 ± 8.76

0.6

HbAc (%)

5.27 ± 0.5

6.7 ± 1.21*

0.002

HOMA-IR

1.53 ± 0.51

2.38 ± 1.39*

0.02

Adiponectin (μg/ml)

10.02 ± 1.1

8.58 ± 1.7*

0.01

IL-6 (pg/ml)

53.17 ± 1.45

77.84 ± 10.98*

0.002

TNF-α (pg/ml)

61.75 ± 6.5

71.63 ± 12.33

0.091

C-reactive protein (mg/dl)

0.86 ± 1.1

0.80 ± 1.4

0.716

FSBF endothelium-dependent (%)

1176.38 ± 531.67

344.59 ± 305.81*

0.037

  1. Data are M ± SD. n=24 control subjects; n=28 GDM subjects and significant difference is as follow: *p<0.05, **p<0.001.