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Table 6 Association of Tanis SNPs with TC in Han and Uygur population

From: Genetic variation in Tanis was associated with elevating plasma triglyceride level in Chinese nondiabetic subjects

  

Mean TC level

Model 1‡

Model 2§

 

Wild/Rare allele

Homozygous for rare allele

Heterozygous

Homozygous for wild allele

P Rec*

P Dom†

P Add※

P Rec*

P Dom†

P Add※

Han

          

rs12910524

C/T

4.11 ± 1.13

4.24 ± 0.95

4.34 ± 0.92

0.047

0.034

0.042

0.062

0.107

0.10

rs1384565

T/C

4.26 ± 1.01

4.30 ± 0.99

4.22 ± 0.99

0.265

0.998

0.510

0.493

0.761

0.692

rs2101171

T/C

4.09 ± 1.01

4.24 ± 0.95

4.26 ± 0.97

0.479

0.330

0.553

0.529

0.142

0.328

rs4965814

T/C

4.17 ± 1.03

4.29 ± 0.98

4.26 ± 0.92

0.955

0.184

0.362

0.757

0.274

0.549

Uygur

          

rs12910524

C/T

3.62 ± 0.99

4.13 ± 0.93

4.28 ± 0.89

<0.001

0.003

<0.001

<0.001

0.005

<0.001

rs1384565

T/C

3.59 ± 1.19

4.15 ± 0.93

4.13 ± 0.94

0.731

0.058

0.163

0.655

0.079

0.213

rs2101171

T/C

4.13 ± 0.94

4.06 ± 0.94

4.38 ± 1.05

0.391

0.622

0.530

0.498

0.535

0.570

rs4965814

T/C

4.08 ± 1.03

4.09 ± 0.97

4.18 ± 0.88

0.310

0.689

0.597

0.361

0.526

0.625

  1. §Analysis of covariance adjusted for sex, age, smoking, alcohol drinking, and GLU; ‡Unadjusted model; *recessive model; †dominant model; ※additive model.
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Lipids in Health and Disease

ISSN: 1476-511X