Enrichment of MTHFR 677 T in a Chinese long-lived cohort and its association with lipid modulation

Table 1 Subject characteristics

	LG (n = 516)	non-LG (n = 493)	F (t or χ²)	P
Age (year)	93.23 ± 2.95	67.19 ± 4.70	104.823	0.000
Male/female	127/389	142/351	2.265	0.132
BMI (kg/m²)	20.40 ± 3.62	21.40 ± 3.11	5.161	0.023
SBP (mmHg)	166.72 ± 27.65	135.87 ± 23.25	1.927	0.165
DBP (mmHg)	89.36 ± 13.58	83.15 ± 11.10	0.931	0.335
TC (mmol/L)	5.15 ± 1.03	4.97 ± 0.96	0.522	0.470
TG (mmol/L)	0.98 (0.48)	0.91 (0.59)	1.979	0.160
HDL-C (mmol/L)	1.60 ± 0.38	1.71 ± 0.41	0.841	0.359
LDL-C (mmol/L)	3.05 ± 0.87	2.73 ± 0.88	0.018	0.892
Dyslipidemia n (%)	261 (50.58)	227 (46.04)	2.078	0.149
Hypertension n (%)	456 (88.37)	231 (46.86)	200.000	0.000

Note: LG, long-lived group; non-LG, non-long-lived group; BMI: body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. TG values were presented as median (interquartile range) while other measures were presented as mean ± SD. The difference between the two groups was determined by analysis of covariance.

ISSN: 1476-511X