Effects of fish oil on serum lipid profile in dialysis patients: a systematic review and meta-analysis of randomized controlled trials

Table 3 Result of subgroup analyses

Subgroup		TG			TC			HDL-C			LDL-C
		Effect size	95% CI	I²(%)	Effect size	95% CI	I²(%)	Effect size	95% CI	I²(%)	Effect size	95% CI	I²(%)
Baseline TG (mmol/L)	≥2.26	−0.56	−0.95, −0.17	66	−0.06	−0.36, 0.23	78	0.33	−0.07, 0.74	97	−0.11	−0.73, 0.51	-
	1.69-2.26	−0.18	−0.30, −0.05	0	−0.15	−0.30, −0.01	20	0.32	−0.27, 0.91	99	−0.08	−0.23, 0.07	76
	≤1.69	−0.24	−0.36, −0.12	0	−0.08	−0.29, 0.13	0	0.01	−0.06, 0.08	0	7	−0.13, 0.26	0
Baseline TC (mmol/L)	>5.17	−0.70	−1.24, −0.16	-	0.18	−0.15, 0.51	0	−0.02	−0.05, 0.01	-	−0.03	−0.15, 0.09	45
Baseline TC (mmol/L)	≤5.17	−0.22	−0.30, −0.13	21	−0.16	−0.28, −0.04	21	0.23	−0.02, 0.48	97	-	-	-
Component of fish oil	EPA	−1.18	−1.99, −0.37	-	−0.88	−1.62, 0.13	0	0.00	−0.13, 0.13	-	-	-	-
Component of fish oil	EPA + DHA	−0.22	−0.31, −0.14	0	−0.09	−0.21, 0.02	12	0.23	0.01, 0.44	97	-	-	-
Dose of EPA + DHA	<2 g	−0.24	−0.35, −0.13	45	−0.15	−0.28, −0.02	40	0.23	0.01, 0.45	97	−0.11	−0.26, 0.03	33
Dose of EPA + DHA	≥2 g	−0.21	−0.34, −0.08	0	−0.06	−0.27, 0.15	0	−0.20	0.01, 0.40	-	0.14	−0.07, 0.34	46
Duration	≤12w	−0.23	−0.32, −0.14	44	−0.11	−0.24, 0.02	37	0.12	−0.01, 0.26	90	0.06	−0.10, 0.23	0
	>12w	−0.24	−0.46, −0.01	0	−0.15	−0.38, 0.07	20	0.44	−0.37, 1.26	97	−0.12	−0.29, 0.04	82

ISSN: 1476-511X