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Figure 8 | Lipids in Health and Disease

Figure 8

From: Twist 1 regulates the expression of PPARγ during hormone-induced 3T3-L1 preadipocyte differentiation: a possible role in obesity and associated diseases

Figure 8

A model for possible role of Twist 1 in obesity or obesity-related diseases. The expression of Twist 1 influences the transcription and protein expression of PPARγ during differentiation induction and alters the secretion of multiple adipokines into the medium, either directly or indirectly. Then, altered PPARγ or adipokines play roles in obesity-related physiological process, but not in adipogenesis, which further regulates obesity or obesity-related diseases.

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