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Table 4 Input and after treatment values for thyroid function parameters, lipid, apolipoprotein levels, apoA1/apoB ratio, AIP and lipoprotein subclasses for hypothyroid patients

From: The effects of treatment on lipoprotein subfractions evaluated by polyacrylamide gel electrophoresis in patients with autoimmune hypothyroidism and hyperthyroidism

 

Hypothyroidism

Before treatment

In euthyreosis

Average

±SD

Min-Max

Average

±SD

Min-Max

Signif.

TC (mmol/l)

6.10

±1.56

2.6-9.2

5.45

±1.03

3.26-7.27

**

TG (mmol/l)

2.05

±1.62

0.7-10.1

1.29

±0.55

0.48-2.5

***

LDL (mmol/l)

3.86

±1.25

1.6-6.4

3.38

±0.85

1.89-5.33

**

HDL (mmol/l)

1.21

±0.31

0.6-2

1.26

±0.31

0.67-1.99

NS

apoA1(g/l)

1.89

±0.65

0.87-3.47

1.67

±0.40

0.77-2.6

*

apoB (g/l)

1.02

±0.29

0.41-1.64

0.92

±0.21

0.56-1.5

**

apoA1/apoB

1.95

±0.71

0.87-3.44

1.86

±0.5

1.16-2.88

NS

AIP

0.17

±0.28

-0.31-0.95

-0.02

±0.26

-0.38-0.47

***

LDL1 (mg/dl)

47.35

±18.48

10-113

53.78

±15.33

32-87

*

LDL2 (mg/dl)

33.85

±19.53

0-76

20.48

±11.25

5-53

***

IDL1 (mg/dl)

24.18

±10.76

8-50

20.93

±6.84

10-36

*

IDL2 (mg/dl)

15.78

±6.88

4-30

13.35

±3.87

8-21

*

IDL3 (mg/dl)

19.38

±9.54

4-43

21.23

±5.21

13-32

NS

VLDL (mg/dl)

40.03

±16.84

8-80

31.20

±9.58

10-61

***

Not-normally distributed variables:

 

Median

Q3-Q1

Min-Max

Median

Q3-Q1

Min-Max

Signif.

TSH (mIU/l)

19.6

27.04

10.57-150

3.21

3,79

0.5-4.8

***

fT4 (pmol/l)

7.24

3.17

1.56-9.0

15

3,41

12-21.8

***

LDL3-7 (mg/dl)

6.5

10

0-54

0

1

0-8

***

  1. apo – apolipoprotein, AIP – atherogenic index of plasma, Q3-Q1 – interquartile range.
  2. * significantly different via the Student’s t-test or Wilcoxon signed-rank test for non-parametric data: * p < 0.05; ** p < 0.01; *** p < 0.001
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Lipids in Health and Disease

ISSN: 1476-511X