Figure 3
From: LDL-cholesterol signaling induces breast cancer proliferation and invasion
LDL induces ERK and akt protein phosphorylation. A. Cells (MDA MB 231) exposed to LDL show higher expression of phosphorylated ERK and akt, without significant increase in respective total protein. Phosphorilation of JNK is also higher, without reaching statistical significance. Epidermal growth factor (EGF) stimulation was used as positive control and induced, as expected, increase ERK, akt and JNK phosphorylation. B. Representative photos of western blot membranes are shown. P value and the number of the experiments are represented in the figure. Columns mean; bars ± SEM.