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Table 4 Summary results for each intervention group – tolerability

From: Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study

Variable

 

Palaeolithic (n 18)

Reference (n 16)

P a

 Differenceb

P c

  

Mean

SD

Mean

SD

   

Haematology

        

Hb (g/l)

      

−1.6 (−6.4;3.2)

0.59

 

Baseline

145.0

11.3

141.8

8.1

0.44

  
 

2 weeks

145.0

11.3

143.4

9.7

   

Ht (l/l)

      

0.00 (−0.01;0.01)

0.93

 

Baseline

0.43

0.03

0.42

0.03

0.40

  
 

2 weeks

0.44

0.03

0.42

0.03

   

RBC (x10E12/l)

     

−0.0 (−0.2;0.1)

0.58

 

Baseline

4.8

0.3

4.8

0.3

0.28

  
 

2 weeks

4.8

0.3

4.7

0.4

   

WBC (x10E9/l)

     

−1.0 (−1.7;-0.2)

0.02

 

Baseline

7.2

1.9

7.1

1.7

0.88

  
 

2 weeks

6.3

1.2

7.0

1.8

   

Platelets (x10E9/l)

      

−15.5 (−35.7;4.7)

0.13

 

Baseline

253.6

44.4

255.1

70.5

094

  
 

2 weeks

240.2

51.5

262.5

72.8

   

Liver and kidney function

      

ASAT (U/l)

     

0.9 (−3.1;4.9)

0.63

 

Baseline

27.6

7.0

26.3

6.8

0.57

  
 

2 weeks

30.6

6.8

25.3

6.6

   

ALAT (U/l)

     

1.9 (−5.5;9.2)

0.61

 

Baseline

35.1

16.8

25.9

11.9

0.08

  
 

2 weeks

38.2

17.7

25.1

10.2

   

GGT (U/l)

      

−9.5 (−17.7;-1.3)

0.03

 

Baseline

27.3

11.1

38.9

39.3

0.24

  
 

2 weeks

21.9

8.1

37.6

40.1

   

AP (U/l)

      

−4.0 (−9.4;1.5)

0.15

 

Baseline

79.3

22.1

70.0

13.3

0.15

  
 

2 weeks

74.1

21.3

70.1

11.5

   

Creatinine (μmol/l)

      

−3.1 (−9.8;3.6)

0.36

 

Baseline

71.2

11.4

76.1

13.0

0.25

  
 

2 weeks

75.6

13.8

79.0

14.6

   

Urea (mmol/l)

      

−0.0 (−0.8;0.8)

0.92

 

Baseline

4.9

1.3

5.1

1.2

0.58

  
 

2 weeks

5.7

1.6

6.0

1.3

   

Other laboratory parameters

      

Urine

        

Sodium (mmol/h)

      

−0.5 (−1.7;0.8)

0.46

 

Baseline

6.3

0.2

6.7

2.9

   
 

2 weeks

3.8

2.7

3.4

1.0

   

Potassium (mmol/h)

      

0.1 (−1.1;1.2)

0.91

 

Baseline

3.5

1.3

4.0

1.6

   
 

2 weeks

3.8

1.5

3.4

1.3

   

Magnesium (mmol/h)

     

−0.04 (−0.07;-0.01)

0.03

 

Baseline

0.14

0.06

0.14

0.06

   
 

2 weeks

0.13

0.08

0.13

0.06

   

Calcium (mmol/h)

      

−0.08 (−0.12;-0.04)

0.00

 

Baseline

0.13

0.13

0.19

0.20

   
 

2 weeks

0.08

0.05

0.16

0.10

   

Sodium:potassium (mmol/mol)

    

−0.20 (−0.62;0.22)

0.34

 

Baseline

2.12

1.16

1.78

0.67

0.31

  
 

2 weeks

1.00

0.47

1.15

0.55

   

Serum

        

Homocysteine (μmol/l)

     

1.05 (−0.44;2.55)

0.16

 

Baseline

11.7

3.9

12.6

3.0

0.31

  
 

2 weeks

12.9

4.3

12.8

3.1

   
  1. Abbreviations: Ht Haematocrit, RBC Red blood cell count, WBC White blood cell count, ASAT Aspartate aminotransferase, ALAT Alanine amino transferase, GGT γ-Glutamyltransferase, AP Alkaline phosphatase.
  2. Mean values and standard deviations, intention-to-treat.
  3. aP values between the two intervention groups at baseline.
  4. bDifference = Palaeolithic-type diet – reference diet (with 95% CI).
  5. cP values between the two intervention groups after the intervention.
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Lipids in Health and Disease

ISSN: 1476-511X