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Table 4 Lipoprotein particle size comparison control and retinoic acid-fed SHR vs. SHR- Lx rats

From: Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model

Trait (nm)

Standard diet

Standard diet + ATRA

SHR

SHR-Lx

SHR

SHR-Lx

 

(n = 7)

(n = 7)

(n = 7)

(n = 8)

VLDL-TG

49.51 ± 0.45

48.24 ± 0.49

48.48 ± 0.68

50.27 ± 0.41*,a

LDL-C

21.45 ± 0.25

21.54 ± 0.11

21.77 ± 0.12

22.52 ± 0.18‡,b

HDL-C

12.20 ± 0.04

12.10 ± 0.03

12.18 ± 0.03

11.93 ± 0.05‡,c

  1. Data are shown as mean ± S.E.M. The significance levels are indicated as follows: a, b, c…p <0.05, 0.01 and 0.001, for differences between SHR and SHR-Lx strains under conditions of a single diet; *, ‡… p <0.05 and 0.001, respectively, for RA effect within individual strain.
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Lipids in Health and Disease

ISSN: 1476-511X