Figure 6From: LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapsesEffects of LDLR knockout on expression of the apoptosis-related genes Bax, Bcl-2 and caspase3 in the hippocampus of C57BL/6 J and Ldlr-/-mice. The data shown are the ratio of protein (A) and mRNA (B) levels of Bax to Bcl-2, the levels of activated-caspase3 protein (C) and caspase-3 mRNA (D) are also quantified in the hippocampus. *P < 0.05, **P < 0.01 for Ldlr-/- vs. C57BL/6 J mice.Back to article page