Groups | Drug concentration (%, w/w) | HDL (mmol/L) | LDL (mmol/L) | HDL/LDL (mmol/L) | LDL/HDL (mmol/L) | N-HDL (mmol/L) |
---|---|---|---|---|---|---|
Normal mice | Â | Â | Â | Â | Â | Â |
Control ND | - | 3.94 ± 0.21 | 0.71 ± 0.04 | 5.82 ± 0.34 | 0.18 ± 0.01 | 0.11 ± 0.11 |
SAqFSC-P/ND | 1 | 3.95 ± 0.09 | 0.67 ± 0.03 | 6.02 ± 0.28 | 0.17 ± 0.01 | 0.23 ± 0.13 |
 | 9 | 4.00 ± 0.11 | 0.63 ± 0.04 | 6.47 ± 0.30 | 0.16 ± 0.01 | 0.25 ± 0.09 |
PAqFSC-P/ND | 1 | 4.00 ± 0.15 | 0.63 ± 0.03 | 6.20 ± 0.36 | 0.16 ± 0.01 | 0.23 ± 0.06 |
 | 9 | 4.18 ± 0.17 | 0.63 ± 0.03 | 6.46 ± 0.29 | 0.16 ± 0.01 | 0.17 ± 0.06 |
Bicyclol/ND | 0.025 | 4.17 ± 0.16 | 0.70 ± 0.04 | 6.21 ± 0.48 | 0.17 ± 0.02 | 0.10 ± 0.07 |
Hypercholester-olemic mice | Â | Â | Â | Â | Â | Â |
Control ND | - | 3.10 ± 0.12 | 0.20 ± 0.02 | 16.65 ± 1.30 | 0.06 ± 0.01 | 0.64 ± 0.03 |
Control HCBD | - | 3.02 ± 0.12 | 1.08 ± 0.07a | 2.86 ± 0.17a | 0.36 ± 0.02a | 2.54 ± 0.14a |
SAqFSC-P/HCBD | 1 | 3.15 ± 0.15 | 1.08 ± 0.06 | 3.29 ± 0.16 | 0.31 ± 0.02 | 2.17 ± 0.12 |
 | 3 | 3.20 ± 0.12 | 1.22 ± 0.09 | 2.90 ± 0.14 | 0.35 ± 0.02 | 2.51 ± 0.19 |
PAqFSC-P/HCBD | 1 | 3.16 ± 0.10 | 1.09 ± 0.06 | 2.72 ± 0.17 | 0.37 ± 0.02 | 2.18 ± 0.10b |
 | 3 | 3.08 ± 0.10 | 0.93 ± 0.05 | 3.30 ± 0.21 | 0.35 ± 0.02 | 1.98 ± 0.11b |
Bicyclol/HCBD | 0.025 | 3.27 ± 0.14 | 1.02 ± 0.07 | 3.41 ± 0.23 | 0.31 ± 0.02 | 2.28 ± 0.13 |