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Table 3 Effects of dietary supplementation with SAqFSC-P, PAqFSC-P, or bicyclol on body weight gain and food/drug intake in normal and hypercholesterolemic mice

From: Dietary pulp from Fructus Schisandra Chinensis supplementation reduces serum/hepatic lipid and hepatic glucose levels in mice fed a normal or high cholesterol/bile salt diet

Groups Drug concentration (%, w/w) Body weight gain (g) Food intake (g/kg/day) Drug intake (g/kg/day)
D 1 → D 5 D 5 → D 10
Normal mice      
Control ND - 7.41 ± 0.29 4.46 ± 0.22 156.4 -
SAqFSC-P/ND 1 7.52 ± 0.07 3.41 ± 0.18a 142.2 1.42
  9 7.19 ± 0.16 3.53 ± 0.27a 157.5 14.18
PAqFSC-P/ND 1 7.42 ± 0.17 3.99 ± 0.36 143.7 1.44
  9 7.49 ± 0.35 4.54 ± 0.26 151.4 13.63
Bicyclol/ND 0.025 7.41 ± 0.20 3.70 ± 0.26a 158.3 0.04
Hypercholesterolemic mice      
Control ND - 10.42 ± 0.25 3.04 ± 0.14 162.7 -
Control HCBD - 9.76 ± 0.16a 2.81 ± 0.12 151.0 -
SAqFSC-P/HCBD 1 9.71 ± 0.29 3.02 ± 0.10 151.4 1.51
  3 9.36 ± 0.20 2.98 ± 0.19 150.0 4.50
PAqFSC-P/HCBD 1 10.02 ± 0.28 2.78 ± 0.11 150.5 1.51
  3 9.66 ± 0.15 3.11 ± 0.16 157.5 4.72
Bicyclol/HCBD 0.025 10.36 ± 0.23 2.72 ± 0.13 152.5 0.04
  1. Experimental details were described in Figure1. The dosages (g/kg/day, based on crude herbal material) were determined with respect to the amount of ingested diet (g/day/kg) and drug concentration in the diet. Values given are the means ± S.E.M., with n = 10. aP < 0.05 vs. control ND, using a one-way ANOVA followed by Dunnett’s multiple comparisons test or post-hoc analysis.