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Table 1 Characteristics of studies included in the meta-analysis

From: Apolipoprotein E gene polymorphism and the risk of intracerebral hemorrhage: a meta-analysis of epidemiologic studies

Study (author, year)

Design

Study period

Population (country)

Genotyping method

No. of cases

No. of controls

Nakata 1997

HCC

1992-1995

Asians (Japan)

PCR

38

38

McCarron 1998

HCC

DNR

Caucasians (United Kingdom)

PCR

71

406

Garcia 1999

PCC

DNR

Caucasians (Portugal)

PCR-RFLP

48

173

Kokubo 2000

PCC

1997-1999

Asians (Japan)

PCR-RFLP

84

1126

Catto 2000

HCC

1997

Caucasians (United Kingdom)

PCR

60

289

Chowdhury 2001

HCC

1998-1999

Asians (Japan)

PCR-RFLP

80

190

Woo 2002

PCC

1997-2000

Caucasians (USA)

PCR

188

366

Woo 2005

HCC

1997-2002

Caucasians (USA)

TaqMan

172

339

Chen 2009

HCC

DNR

Asians (China)

PCR

217

280

Zhang 2012

HCC

2008-2010

Asians (China)

PCR-RFLP

180

180

Misra 2012

HCC

DNR

Asians (India)

PCR

100

188

  1. Abbreviations: HCC Hospital-based case–control, PCC Population-based case–control, DNR Data not reported, PCR Polymerase chain reaction, RFLP Restriction fragment length polymorphism.