Table 2 Genotypic distribution of APOA5 polymorphisms and statistic comparison between AHT subjects and controls

-1131 T > C

Codominant

TT

128 (95.5%)

97 (65.1%)

1.00

TC

2 (1.5%)

20 (13.4%)

11.16 (2.46-50.69)

0.002

0.006 ^*

CC

4 (3%)

32 (21.5%)

14.20 (4.50-44.77)

<0.0001

<0.0001 ^*

Dominant

TT

128 (95.5%)

97 (65.1%)

1.00

TC/CC

6 (4.5%)

52 (34.9%)

13.20 (5.14-33.91)

<0.0001

<0.0001 ^*

Recessive

TT/TC

130 (97%)

117 (78.5%)

1.00

CC

4 (3%)

32 (21.5%)

12.35 (3.91-39.05)

<0.0001

<0.0001 ^*

56C > G

Codominant

CC

117 (87.3%)

106 (71.1%)

1.00

CG

15 (11.2%)

21 (14.1%)

1.54 (0.72-3.29)

0.269

NS

GG

2 (1.5%)

22 (14.8%)

13.75 (3.01-62.75)

0.001

0.003 ^*

Dominant

CC

117 (87.3%)

106 (71.1%)

1.00

CG/GG

17 (12.7%)

43 (28.9%)

2.90 (1.49-5.63)

0.002

0.006 ^*

Recessive

CC/CG

132 (98.5%)

127 (85.2%)

1.00

GG

2 (1.5%)

22 (14.8%)

12.77 (2.82-57.73)

0.001

0.003 ^*

c.553G > T

Codominant

GG

130 (97%)

132 (88.6%)

1.00

GT

3 (2.2%)

15 (10.1%)

4.72 (1.28-17.35)

0.020

NS

TT

1 (0.8%)

2 (1.3%)

1.64 (0.14-19.78)

0.695

NS

Dominant

GG

130 (97%)

132 (88.6%)

1.00

GT/TT

4 (3%)

17 (11.4%)

3.92 (1.23-12.43)

0.02

NS

Recessive

GG/GT

133 (99.2%)

147 (98.7%)

1.00

TT

1 (0.8%)

2 (1.3%)

1.47 (0.12-17.70)

0.763

NS