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Table 5 Association between APOA5 haplotypes and clinical and biochemical parameters

From: Association of APOA5 rs662799 and rs3135506 polymorphisms with arterial hypertension in Moroccan patients

 

Haplotype H1 (TCG)

Haplotype H2 (CCG)

Haplotype H3 (TGG)

Haplotype H4 (CGG)

 

Present

Not present

P value

Present

Not present

P value

Present

Not present

P value

Present

Not present

P value

Age (years)

55.10 ± 12.36

57.52 ± 14.00

0.2276

56.97 ± 13.12

55.33 ± 12.62

0.4976

57.03 ± 14.38

55.33 ± 12.46

0.4865

57.50 ± 12.69

55.25 ± 12.66

0.3458

Sbp (mmgHg)

134.79 ± 19.84

155.00 ± 21.55

<0.0001**

152.55 ± 17.19

136.46 ± 21.33

<0.0001**

139.10 ± 21.19

138.11 ± 21.56

0.7795

157.56 ± 21.21

135.75 ± 20.27

<0.0001**

Dbp (mmgHg)

81.03 ± 10.41

86.48 ± 9.88

0.001**

86.35 ± 8.47

81.41 ± 10.62

0.0132*

81.40 ± 16.88

82.02 ± 9.52

0.7606

87.88 ± 8.59

81.20 ± 10.50

0.0006**

BMI (kg/m2)

26.85 ± 4.30

27.64 ± 4.90

0.2596

26.50 ± 4.67

27.04 ± 4.38

0.5181

27.11 ± 4.88

26.97 ± 4.36

0.8684

28.12 ± 5.56

26.83 ± 4.23

0.1195

TG (g/L)

1.24 ± 0.65

1.81 ± 0.92

<0.0001**

1.38 ± 0.69

1.33 ± 0.74

0.497

1.61 ± 1.00

1.31 ± 0.69

0.1055

1.99 ± 0.98

1.25 ± 0.65

<0.0001**

LDL(g/L)

1.23 ± 0.37

1.36 ± 0.47

0.0402*

1.42 ± 0.46

1.23 ± 0.38

0.0107*

1.24 ± 0.43

1.25 ± 0.39

0.8132

1.36 ± 0.45

1.24 ± 0.38

0.0883

HDL(g/L)

0.51 ± 0.16

0.45 ± 0.10

0.0061*

0.48 ± 0.10

0.50 ± 0.16

0.4389

0.47 ± 0.14

0.51 ± 0.16

0.2057

0.47 ± 0.12

0.51 ± 0.16

0.1585

Gly (g/L)

1.07 ± 0.46

1.12 ± 0.39

0.2406

1.16 ± 0.49

1.07 ± 0.44

0.1619

0.99 ± 0.21

1.09 ± 0.47

0.6938

1.08 ± 0.33

1.08 ± 0.46

0.5571

TC (g/L)

1.98 ± 0.41

2.15 ± 0.54

0.0122*

2.15 ± 0.53

1.99 ± 0.42

0.0604

2.00 ± 0.48

2.01 ± 0.43

0.8825

2.18 ± 0.54

1.98 ± 0.42

0.0162*

  1. *P values not significant after Bonferroni correction.
  2. **P values remains significant after Bonferroni correction.