Table 6 Differences in genotype frequencies of five SNPs according to the subject’s plasma LDL-C response to an n-3 PUFA supplementation
SNP | Homozygotes (wild-type) | Heterogygotes | Homozygotes (rare) | p1 | |||
|---|---|---|---|---|---|---|---|
P-Responders | N-responders | P-Responders | N-responders | P-Responders | N-responders | ||
rs782440 | 23 (11%) | 30 (14%) | 56 (27%) | 47 (23%) | 15 (7%) | 37 (18%) | 0.01 |
rs555183 | 27 (13%) | 42 (20%) | 54 (26%) | 46 (22%) | 13 (6%) | 26 (13%) | 0.04 |
rs6780384 | 68 (33%) | 99 (47%) | 26 (13%) | 13 (6%) | 0 (0%) | 2 (1%) | 0.006 |
rs782444 | 23 (11%) | 48 (23%) | 48 (23%) | 45 (22%) | 23 (11%) | 21 (10%) | 0.03 |
rs6787155 | 49 (24%) | 80 (38%) | 38 (18%) | 27 (13%) | 7 (3%) | 7 (3%) | 0.02 |