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Table 6 Differences in genotype frequencies of five SNPs according to the subject’s plasma LDL-C response to an n-3 PUFA supplementation

From: Gene-diet interactions with polymorphisms of the MGLL gene on plasma low-density lipoprotein cholesterol and size following an omega-3 polyunsaturated fatty acid supplementation: a clinical trial

SNP Homozygotes (wild-type) Heterogygotes Homozygotes (rare) p1
P-Responders N-responders P-Responders N-responders P-Responders N-responders
rs782440 23 (11%) 30 (14%) 56 (27%) 47 (23%) 15 (7%) 37 (18%) 0.01
rs555183 27 (13%) 42 (20%) 54 (26%) 46 (22%) 13 (6%) 26 (13%) 0.04
rs6780384 68 (33%) 99 (47%) 26 (13%) 13 (6%) 0 (0%) 2 (1%) 0.006
rs782444 23 (11%) 48 (23%) 48 (23%) 45 (22%) 23 (11%) 21 (10%) 0.03
rs6787155 49 (24%) 80 (38%) 38 (18%) 27 (13%) 7 (3%) 7 (3%) 0.02
  1. 1chi-square test in SAS 9.2.
  2. P (positive) responders versus N (negative) responders.