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Table 4 Multivariate associations of the rs2302685 in LRP6 gene with the risk of MI by further stratification for age

From: The LRP6 rs2302685 polymorphism is associated with increased risk of myocardial infarction

Type

Controls no. (%)

Cases no. (%)

OR (95% CI)a

P-valuea

≤60 y

n = 297

n = 130

 

T

553 (93.1)

233 (89.6)

1.00

-

C

41 (6.9)

27 (10.4)

2.46 (1.20-5.03)

0.014 b

TT

256 (86.2)

104 (80.0)

1.00

-

CT + CC

41 (13.8)

26 (20.0)

2.46 (1.19-5.06)

0.015

> 60 y

n = 353

n = 155

 

T

664 (94.1)

291 (93.9)

1.00

-

C

42 (5.9)

19 (6.1)

1.16 (0.62-2.19)

0.636

TT

313 (88.7)

136 (87.7)

1.00

-

CT + CC

40 (11.3)

19 (12.3)

1.22 (0.63-2.35)

0.557

  1. aAdjusted for sex, smoking, drinking, hypertension, diabetes and hyperlipidemia.
  2. bP values under 0.05 were indicated in bold font.