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Table 3 Kinetic parameters of LDL, LDL + HDL2 and LDL + HDL3 oxidation in 59 healthy subjects.

From: HDL enhances oxidation of LDL in vitro in both men and women

  Women Men All
LDL    
Lag time (min) 60.9 ± 7.9 59.3 ± 6.9 60.2 ± 7.4
Rate (μmol/l/min)a 0.509 ± 0.067 0.502 ± 0.067 0.506 ± 0.066
Max (nmol/mg)b 541 ± 41 537 ± 51 539 ± 45
LDL + HDL 2    
Lag time (min) 56.0 ± 5.7*** 56.0 ± 6.7*** 56.0 ± 6.1***
Rate (μmol/l/min)a 0.687 ± 0.062*** 0.654 ± 0.084*** 0.671 ± 0.073***
Max (nmol/mg)b 774 ± 40*** 745 ± 71*** 762 ± 56***
LDL + HDL 3    
Lag time (min) 55.8 ± 5.4*** 54.8 ± 5.4*** 55.3 ± 5.4***
Rate (μmol/l/min)a 0.616 ± 0.064*** 0.607 ± 0.070*** 0.612 ± 0.066***
Max (nmol/mg)b 687 ± 40*** 674 ± 60*** 681 ± 50***
  1. Values are mean ± SD. a Rate means maximal formation rate of conjugated dienes during oxidation. Calculation of the diene concentration is based on ε = 29500 of the conjugated dienes b Max is the maximal amount of dienes produced per mg of LDL protein. *** p < 0.001 in comparison with LDL alone in Wilcoxon's matched pairs test.