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Table 1 Concentration of selected fatty acids in cardiolipin and ethanolamine glycerophospholipids of 4, 12 and 24 month old rat hearts

From: Selective remodeling of cardiolipin fatty acids in the aged rat heart

  Cardiolipin Ethanolamine Glycerophospholipids
Fatty Acid 4 Months 12 Months 24 Months 4 Months 12 Months 24 Months
Palmitic acid (16:0) 44 ± 7a 62 ± 15 64 ± 15 * 1166 ± 150 1426 ± 297 1135 ± 129
Stearic acid (18:0) 47 ± 4 49 ± 10 47 ± 14 3943 ± 327 4068 ± 806 3295 ± 373
Oleic acid (18:1n-9) 279 ± 42 291 ± 53 347 ± 57 394 ± 46 372 ± 88 349 ± 30
Linoleic acid (18:2n-6) 5525 ± 656 6025 ± 1094 3965 ± 617 ** 1032 ± 168 864 ± 158 * 459 ± 129 ***
Arachidonic acid (20:4n-6) 79 ± 9 140 ± 54 * 178 ± 27 *** 2625 ± 155 2662 ± 595 2346 ± 260
Docosahexaenoic acid (22:6n-3) 104 ± 16 230 ± 95 * 307 ± 68 *** 3511 ± 279 4436 ± 899 * 3576 ± 326
Σ Of major fatty acids 8374 ± 650 8652 ± 1278 7107 ± 845 * 12672 ± 1032 132829 ± 2796 11161 ± 1002
  1. a Data are mean ± SD, n = 6 samples per group, nmol/g wet weight *, p < 0.05, **p < 0.01, ***p < 0.001 vs 4 Months.