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Table 1 Varying degrees of intimal thickening, serum lipids, and CRP in rabbits fed cholesterol supplement for 3 months.

From: Accumulation of low density lipoprotein associated cholesterol in calcifying vesicle fractions correlates with intimal thickening in thoracic aortas of juvenile rabbits fed a supplemental cholesterol diet

Measurements

Chow fed rabbits

Cholesterol diet rabbits

 
 

M ± SD (n)

Ranges

M ± SD (n)

Ranges

p values

Intima/media

0 (9)

0

0.31 ± 0.37 (14)

0–1.0

<0.0001

Cholesterol (mg/dl)

18 ± 5 (9)

11–25

2200 ± 1196 (14)

725–4865

<0.0001

Triglyceride (mg/dl)

79 ± 46 (9)

13–148

365 ± 396 (14)

15–1365

0.045

HDL (mg/dl)

<5 (9)

<5

282 ± 209 (14)

50–680

<0.0001

LDL (mg/dl)

<10 (9)

<10

610 ± 263 (14)

240–1280

<0.0001

CRP (ng/ml)

230 ± 192 (6)

98–606

1193 ± 948 (12)

212–3184

0.027

  1. The data are means ± S.D. (numbers of rabbits). The p values show the statistical significance of differences of each parameter between cholesterol-fed and control rabbits.
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Lipids in Health and Disease

ISSN: 1476-511X