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Table 1 Varying degrees of intimal thickening, serum lipids, and CRP in rabbits fed cholesterol supplement for 3 months.

From: Accumulation of low density lipoprotein associated cholesterol in calcifying vesicle fractions correlates with intimal thickening in thoracic aortas of juvenile rabbits fed a supplemental cholesterol diet

Measurements Chow fed rabbits Cholesterol diet rabbits  
  M ± SD (n) Ranges M ± SD (n) Ranges p values
Intima/media 0 (9) 0 0.31 ± 0.37 (14) 0–1.0 <0.0001
Cholesterol (mg/dl) 18 ± 5 (9) 11–25 2200 ± 1196 (14) 725–4865 <0.0001
Triglyceride (mg/dl) 79 ± 46 (9) 13–148 365 ± 396 (14) 15–1365 0.045
HDL (mg/dl) <5 (9) <5 282 ± 209 (14) 50–680 <0.0001
LDL (mg/dl) <10 (9) <10 610 ± 263 (14) 240–1280 <0.0001
CRP (ng/ml) 230 ± 192 (6) 98–606 1193 ± 948 (12) 212–3184 0.027
  1. The data are means ± S.D. (numbers of rabbits). The p values show the statistical significance of differences of each parameter between cholesterol-fed and control rabbits.
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Lipids in Health and Disease

ISSN: 1476-511X