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Table 1 Radioactivity measurements in lipid extracts of intestine, stomach and liver after oral administration of 3H-sulfatide

From: Uptake of the glycosphingolipid sulfatide in the gastrointestinal tract and pancreas in vivo and in isolated islets of Langerhans

Hours after sulfatide load

Stomach dpm/mg protein

Duodenum/Jejunum dpm/mg protein

Ileum dpm/mg protein

Terminal ileum dpm/mg protein

Liver dpm/mg protein

1–2

6210 ± 1203 (8)

360 ± 58 (8)

1208 ± 238 (8)

2973 ± 2290 (3)

7 ± 2 (5)

5–6

522 ± 145 (7)**

222 ± 47 (7) (n.s.)

473 ± 115 (7)*

523 ± 93 (7) (n.s.)

15 ± 3 (7) (n.s.)

24

n.d. (3)

40 ± 10 (7)**

55 ± 8 (4)**

40 ± 10 (4)**

n.d (3)

   

n.d. (3)

n.d. (3)

 
  1. BALB/c mice received sulfatide (250 nmol-1 μmol/mL, 1.7 × 106 dpm/mouse of 3H-sulfatide) orally, whereafter the animals were sacrificed after 1–2 hours (n = 8), 5–6 hours (n = 7) or 24 hours (n = 7). Values are mean ± SEM (n). * p < 0.05; ** p < 0.01, where 1–2 h are compared to 5–6 h after sulfatide load and 5–6 h are compared to 24 h after sulfatide load. n.d. = not detected, n.s. = not significant.
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Lipids in Health and Disease

ISSN: 1476-511X