Table 1 The effect of ProAlgaZyme on various parameters related to metabolic syndrome. Bolded values represent mean Δ after 10* weeks of treatment ± (1.96*SEM) for a 95% confidence level. Values in parentheses are mean starting values (at T = 0) ± (1.96*SEM). Significance indicates comparison of changes after 10* weeks of treatment with PAZ to placebo. A negative value indicates a decrease, while a positive value indicates an increase over the test period. *Values for RBC sedimentation, triglycerides, LDL-C and blood pressure are after 8 weeks of treatment. NS = Not significant.

Weight (kg)

-4.18 ± 0.76

(86.70 ± 2.31)

-1.20 ± 0.29

(86.34 ± 2.61)

P < 0.001

BMI (kg/m²)

-1.51 ± 0.28

(31.13 ± 0.62)

-0.20 ± 0.11

(31.95 ± 0.63)

P < 0.001

Body fat (%)

-2.46 ± 3.51

(40.14 ± 0.79)

-0.30 ± 0.17

(41.88 ± 1.11)

P < 0.001

Blood pressure (Sys⁸, mm Hg)

-10.32 ± 2.69

(152.23 ± 4.41)

-1.36 ± 2.18

(158.21 ± 4.39)

P < 0.01

Blood pressure (Dias⁸, mm Hg)

-7.27 ± 2.50

(68.73 ± 2.58)

-2.32 ± 1.84

(72.82 ± 2.69)

P < 0.001

Insulin (uIU/mL)

1.28 ± 2.34

(23.48 ± 2.23)

-1.01 ± 1.57

(23.02 ± 3.18)

NS

Fasting blood glucose (mg/dL)

-18.50 ± 5.56

(98.72 ± 5.65)

-0.58 ± 2.11

(98.41 ± 3.41)

P < 0.001

Total cholesterol (mg/dL)

-64.84 ± 9.68

(201.94 ± 3.92)

-5.45 ± 2.51

(204.17 ± 3.87)

P < 0.001

HDL cholesterol (mg/dL)

15.37 ± 3.04

(37.02 ± 1.07)

-2.98 ± 1.53

(38.76 ± 1.44)

P < 0.001

LDL cholesterol⁸ (mg/dL)

-40.63 ± 9.58

(131.32 ± 3.73)

-0.69 ± 2.79

(131.45 ± 4.15)

P < 0.001

Triglycerides⁸ (mg/dL)

-18.77 ± 6.18

(167.95 ± 7.35)

-1.96 ± 4.52

(166.67 ± 4.64)

P < 0.001

RBC sed. rate⁸ (mm/h)

-3.05 ± 0.78

(14.23 ± 0.58)

-0.25 ± 0.65

(14.36 ± 0.68)

P < 0.001

C-reactive protein (mg/L)

-6.20 ± 0.92

(10.83 ± 0.51)

-0.83 ± 0.49

(11.41 ± 0.67)

P < 0.001

Interleukin-6 (pg/mL)

-3.62 ± 1.03

(14.40 ± 2.01)

-0.03 ± 0.26

(12.65 ± 1.20)

P < 0.001

TNF-a (pg/mL)

-0.65 ± 0.66

(11.22 ± 1.14)

-0.08 ± 0.44

(10.95 ± 0.84)

P < 0.05