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Figure 2 | Lipids in Health and Disease

Figure 2

From: Feeding oxidized fat during pregnancy up-regulates expression of PPARα-responsive genes in the liver of rat fetuses

Figure 2

Effects of treatment on relative mRNA concentrations of SREBP-1c and FAS in livers of pregnant rats and fetuses. Effect of short-term (d 16 – d 21 of pregnancy, left) and long-term (d 1 – d 21 of pregnancy, right) administration of three different diets (control, oxidized fat, clofibrate) during pregnancy on relative mRNA concentrations of SREBP-1c and FAS in the liver of pregnant rats and fetuses at d 21 of pregnancy. Left, Bars represent mean ± SD (n = 9/group). Right, Bars represent mean ± SD (n = 12/group). Bars marked without a common superscript letter differ (P < 0.05). Results from one-way ANOVA (P-values): short-term experiment: SREBP-1c, P = 0.041 (pregnant), P = 0.058 (fetus); FAS, P = 0.026 (pregnant), P = 0.425 (fetus); long-term experiment: SREBP-1c, P = 0.526 (pregnant), P = 0.189 (fetus); FAS, P = 0.716 (pregnant), P = 0.334 (fetus).

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Lipids in Health and Disease

ISSN: 1476-511X