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Table 1 Clinical and biochemical characteristics of controls, patients with CLD and CKD.

From: Isoforms of Retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liver

 

Controls

CLD

CKD

N (m/f)

50 (27/23)

55 (30/25)

36 (26/10)

Age (years)

55.0 (48.2 – 60.0)

50.0 (44.0 – 58.0)

59.0 (45.3 – 68.8)

BMI (kg/m2)

24.4 (22.5 – 26.2)

24.0 (21.3 – 25.9)

25.3 (22.2 – 27.7)

Glucose (mmoL/L)

4.73 (4.45 – 5.17)

5.27 (4.82 – 5.94) *

5.24 (4.63 – 5.94) *

CRP (nmoL/L)

0.0 (0.0 – 0.0)

43.5 (39.3 – 52.1) *

342.9 (104.8 – 800.0) * #

Creatinine (μmoL/L)

68.8 (63.5 – 75.5)

63.3 (55.7 – 73.9) *

239.4 (180.0 – 528.4) * #

Protein (g/L)

66.5 (63.5 – 70.2)

50.7 (45.2 – 57.1) *

65.0 (59.0 – 70.0) #

AST [μkat/L]

0.35 (0.28 – 0.40)

0.89 (0.36 – 1.51) *

0.30 (0.24 – 0.43)#

ALT [μkat/L]

0.17 (0.12 – 0.24)

0.82 (0.55 – 1.39) *

0.37 (0.21 – 0.52) * #

ALP [μkat/L]

1.06 (0.79 – 1.31)

1.73 (0.99 – 2.48) *

1.32 (0.97 – 1.62) *

GGT [μkat/L]

0.30 (0.21 – 0.43)

1.03 (0.44 – 2.21) *

0.53 (0.32 – 1.41) *

Haemotocrit

0.41 (0.38 – 0.44)

0.42 (0.38 – 0.46)

0.32 (0.29 – 0.37) * #

Haemoglobin (g/L)

138.5 (130.0 – 149.8)

145.0 (126.8 – 155.3)

107.5 (97.5 – 125.0) * #

  1. Data are expressed as median with 25th and 75th percentiles. BMI, body mass index; CRP, C-reactive protein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase.
  2. * = significantly different from controls (p < 0.05). # = significantly different from CLD (p < 0.05).