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Table 1 Clinical and biochemical characteristics of controls, patients with CLD and CKD.

From: Isoforms of Retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liver

  Controls CLD CKD
N (m/f) 50 (27/23) 55 (30/25) 36 (26/10)
Age (years) 55.0 (48.2 – 60.0) 50.0 (44.0 – 58.0) 59.0 (45.3 – 68.8)
BMI (kg/m2) 24.4 (22.5 – 26.2) 24.0 (21.3 – 25.9) 25.3 (22.2 – 27.7)
Glucose (mmoL/L) 4.73 (4.45 – 5.17) 5.27 (4.82 – 5.94) * 5.24 (4.63 – 5.94) *
CRP (nmoL/L) 0.0 (0.0 – 0.0) 43.5 (39.3 – 52.1) * 342.9 (104.8 – 800.0) * #
Creatinine (μmoL/L) 68.8 (63.5 – 75.5) 63.3 (55.7 – 73.9) * 239.4 (180.0 – 528.4) * #
Protein (g/L) 66.5 (63.5 – 70.2) 50.7 (45.2 – 57.1) * 65.0 (59.0 – 70.0) #
AST [μkat/L] 0.35 (0.28 – 0.40) 0.89 (0.36 – 1.51) * 0.30 (0.24 – 0.43)#
ALT [μkat/L] 0.17 (0.12 – 0.24) 0.82 (0.55 – 1.39) * 0.37 (0.21 – 0.52) * #
ALP [μkat/L] 1.06 (0.79 – 1.31) 1.73 (0.99 – 2.48) * 1.32 (0.97 – 1.62) *
GGT [μkat/L] 0.30 (0.21 – 0.43) 1.03 (0.44 – 2.21) * 0.53 (0.32 – 1.41) *
Haemotocrit 0.41 (0.38 – 0.44) 0.42 (0.38 – 0.46) 0.32 (0.29 – 0.37) * #
Haemoglobin (g/L) 138.5 (130.0 – 149.8) 145.0 (126.8 – 155.3) 107.5 (97.5 – 125.0) * #
  1. Data are expressed as median with 25th and 75th percentiles. BMI, body mass index; CRP, C-reactive protein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase.
  2. * = significantly different from controls (p < 0.05). # = significantly different from CLD (p < 0.05).