Table 4 Clinical and metabolic characteristics of the hFH-N men and women (subgroup hFH-N).
| Â | hFH-N men n = 17 | hFH-N women n = 18 | p |
|---|---|---|---|
Age (years) | 33.0(13.5) | 55.5(13.8) | < 0.01 |
BMI (kg/m2) | 24.5(2.9) | 22.8(4.1) | < 0.01 |
Waist (cm) | 91.0(13.0) | 76.0(13.0) | < 0.01 |
TC (mg/dl) | 292.0(64.0) | 331.0(59.3) | 0.08 |
TG0 (mg/dl) | 76.0(30.5) | 76.0(38.8) | 0.91 |
TG2 (mg/dl) | 128.5(24.8) | 112.0(54.5) | 0.25 |
TG4 (mg/dl) | 145.5(63.5) | 132.0(78.5) | 0.21 |
TG6 (mg/dl) | 131.0(60.5) | 126.0(64.3) | 0.96 |
TG8 (mg/dl) | 103.0(57.5) | 99.5(66.8) | 0.46 |
TG AUC (mg/dl/h) | 990.3(335.0) | 874.0(351.6) | 0.37 |
TG i-AUC (mg/dl/h) | 377.3(161.5) | 312.8(235.8) | 0.17 |
HDL (mg/dl) | 48.0(18.5) | 60.0(24.0) | 0.02 |
LDL (mg/dl) | 232.0(66.5) | 254.5(58.0) | 0.26 |
Apo AI (mg/dl) | 137.5(41.7) | 158.4(45.8) | 0.09 |
Apo B (mg/dl) | 146.8(41.0) | 158.5(40.1) | 0.26 |
Lp (a) (mg/dl) | 16.0(18.5) | 18.4(28.8) | 0.65 |
Glu (mg/dl) | 82.0(11.5) | 89.0(12.5) | 0.35 |
TaqIB allele frequency, n (%) | Â | Â | Â |
B1 | 17 (50.0) | 20 (55.6) | 0.64 |
B2 | 17 (50.0) | 16 (44.4) | Â |
I405V allele frequency, n (%) | Â | Â | Â |
I | 21 (61.8) | 22 (61.1) | 0.96 |
V | 13 (38.2) | 14 (38.9) | Â |
S447X allele frequency, n (%) | Â | Â | Â |
S | 31 (91.2) | 31 (86.1) | 0.51 |
X | 3 (8.8) | 5 (13.9) | Â |