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Figure 2 | Lipids in Health and Disease

Figure 2

From: Novel point mutations attenuate autotaxin activity

Figure 2

Substrate selectivity of H226Q and H434Q. Hydrolyses were detected as described in Methods. Reactions contained 60 ng ATX protein and product accumulation was read beginning at 30 minutes and at intervals thereafter as indicated. A. [LPC] = 125 μM. B. [FS-3] = 6 μM. C. [pNpTMP] = 4 mM. WT: wild type; 420: H420Q; 434: H434Q; 226: H226Q.

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Lipids in Health and Disease

ISSN: 1476-511X