Figure 5
From: Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia
Schematic diagram of the proposed mechanisms of ezetimibe-induced atheroprotective effects. LDL-C, low-density lipoprotein-cholesterol; ox-LDL, oxidized LDL; VEGF, vascular endothelial growth factor; LPS, lipopolysaccharide; MCP-1, monocyte chemotactic protein-1; CM, chylomicrons; TG, triglyceride; HDL-C, high-density lipoprotein-cholesterol; NAFLD, non-alcoholic fatty liver disease; NPC1L1, Nieman-Pick C1-like 1; apoB, apolipoprotein B; VLDL, very-low density lipoprotein; JNK, Janus-family tyrosine kinase.