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Table 1 Baseline characteristics across quartiles of lipid accumulation product among men.

From: Predictive performances of lipid accumulation product vs. adiposity measures for cardiovascular diseases and all-cause mortality, 8.6-year follow-up: Tehran lipid and glucose study

 

Q1 (cm.mmol.l-1) <2288

Q2 (cm.mmol.l-1) 2289-4186

Q3 (cm.mmol.l-1) 4192-6900

Q4 (cm.mmol.l-1) 6912-57000

P for trends†

Number of participants*

741

741

742

740

 

Age (years)

48.1(14.4)

49.1(13.6)

50.7(13.0)

49.2(12.5)

 

SBP (mmHg)

117.2(19.8)

122.0(19.3)

126.8(20.9)

127.6(19.0)

<0.001

DBP (mmHg)

73.9(11.5)

77.9(10.6)

81.1(11.2)

82.0(11.2)

<0.001

MAP (mmHg)

88.3(12.8)

92.6(12.2)

96.4(13.1)

97.2(12.6)

<0.001

Pulse pressure (mmHg)

43.3(16.1)

44.1(15.0)

45.7(16.0)

45.5(14.1)

<0.001

Pulse (beat per minute)

73.1(10.0)

73.6(9.9)

75.1(9.5)

76.3(9.7)

<0.001

BMI (kg.m-2)

22.4(2.8)

25.7(2.7)

27.6(2.8)

29.3(3.5)

<0.001

Waist-to-hip ratio (%)

86.2(5.5)

92.9(5.2)

95.9(5.3)

98.3(5.6)

<0.001

Waist-to-height ratio (%)

46.5(4.6)

52.9(4.4)

56.0(4.4)

58.8(5.2)

<0.001

Lipid accumulation product

11.4(2.2)

35.9(1.2)

60.3(1.2)

117.9(1.4)

<0.001

Triglycerides (mmol.l-1)

1.1(1.4)

1.6(1.5)

2.1(1.3)

3.5(1.5)

<0.001

Total cholesterol (mmol.l-1)

4.9(1.0)

5.3(0.9)

5.6(1.0)

6.0(1.2)

<0.001

Non-HDL-C (mmol.l-1)

3.8(0.9)

4.3(0.9)

4.6(0.9)

5.2(1.1)

<0.001

HDL-C (mmol.l-1)

1.1(0.3)

1.0(0.2)

1.0(0.2)

0.9(0.2)

<0.001

FPG (mmol.l-1)

5.2(1.4)

5.4(1.5)

5.6(1.7)

6.1(2.3)

<0.001

2h-PCPG (mmol.l-1)

5.5(2.6)

6.4(3.2)

6.9(3.5)

8.0(4.2)

<0.001

Assignment to intervention (%)

288 (38.9)

281 (37.9)

275 (37.1)

305 (41.2)

0.347

Diabetes

59 (8.0)

76 (10.3)

146 (19.7)

205 (27.7)

<0.001

Hypertension

253 (34.1)

366 (49.4)

462 (62.3)

476 (64.3)

<0.001

Smoking

253 (34.1)

202 (27.3)

176 (23.7)

208 (28.1)

0.001

Family history of premature CVD

49 (6.6)

58 (7.8)

70 (4.9)

61 (8.2)

0.223

Incident** CHD (95% CIs)

5.3(3.8-7.6)

8.6(6.5-11.5)

11.2(8.7-14.4)

15.0(12.1-18.6)

<0.001

Incident** CVD (95% CIs)

6.9(5.1-9.4)

10.1(7.8-13.2)

13.2(10.4-16.6)

17.0(13.8-20.8)

<0.001

Mortality** rate (95% CIs)

8.3(6.3-11.0)

7.6(5.7-10.2)

6.1(4.4-8.4)

5.8(4.2-8.1)

0.134

  1. BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL, high density lipoprotein cholesterol; MAP, mean arterial pressure 2h-PCPG, 2-hour post-challenge plasma glucose; SBP, systolic blood pressure;.
  2. Continuous variables are represented as mean (standard deviation) except for triglycerides and lipid accumulation products that are represented as geometric mean (standard deviation of geometric mean). Categorical variables are represented as frequency (percent). Confidence intervals have been provided for incident rates.
  3. **Per 1000 person per year
  4. † P-values were calculated using general linear models, for continuous variables and Cox proportional hazards regression models for incidence rates. Models were sex-specific and age-adjusted.
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Lipids in Health and Disease

ISSN: 1476-511X