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Table 1 Baseline characteristics across quartiles of lipid accumulation product among men.

From: Predictive performances of lipid accumulation product vs. adiposity measures for cardiovascular diseases and all-cause mortality, 8.6-year follow-up: Tehran lipid and glucose study

  Q1 (cm.mmol.l-1) <2288 Q2 (cm.mmol.l-1) 2289-4186 Q3 (cm.mmol.l-1) 4192-6900 Q4 (cm.mmol.l-1) 6912-57000 P for trends
Number of participants* 741 741 742 740  
Age (years) 48.1(14.4) 49.1(13.6) 50.7(13.0) 49.2(12.5)  
SBP (mmHg) 117.2(19.8) 122.0(19.3) 126.8(20.9) 127.6(19.0) <0.001
DBP (mmHg) 73.9(11.5) 77.9(10.6) 81.1(11.2) 82.0(11.2) <0.001
MAP (mmHg) 88.3(12.8) 92.6(12.2) 96.4(13.1) 97.2(12.6) <0.001
Pulse pressure (mmHg) 43.3(16.1) 44.1(15.0) 45.7(16.0) 45.5(14.1) <0.001
Pulse (beat per minute) 73.1(10.0) 73.6(9.9) 75.1(9.5) 76.3(9.7) <0.001
BMI (kg.m-2) 22.4(2.8) 25.7(2.7) 27.6(2.8) 29.3(3.5) <0.001
Waist-to-hip ratio (%) 86.2(5.5) 92.9(5.2) 95.9(5.3) 98.3(5.6) <0.001
Waist-to-height ratio (%) 46.5(4.6) 52.9(4.4) 56.0(4.4) 58.8(5.2) <0.001
Lipid accumulation product 11.4(2.2) 35.9(1.2) 60.3(1.2) 117.9(1.4) <0.001
Triglycerides (mmol.l-1) 1.1(1.4) 1.6(1.5) 2.1(1.3) 3.5(1.5) <0.001
Total cholesterol (mmol.l-1) 4.9(1.0) 5.3(0.9) 5.6(1.0) 6.0(1.2) <0.001
Non-HDL-C (mmol.l-1) 3.8(0.9) 4.3(0.9) 4.6(0.9) 5.2(1.1) <0.001
HDL-C (mmol.l-1) 1.1(0.3) 1.0(0.2) 1.0(0.2) 0.9(0.2) <0.001
FPG (mmol.l-1) 5.2(1.4) 5.4(1.5) 5.6(1.7) 6.1(2.3) <0.001
2h-PCPG (mmol.l-1) 5.5(2.6) 6.4(3.2) 6.9(3.5) 8.0(4.2) <0.001
Assignment to intervention (%) 288 (38.9) 281 (37.9) 275 (37.1) 305 (41.2) 0.347
Diabetes 59 (8.0) 76 (10.3) 146 (19.7) 205 (27.7) <0.001
Hypertension 253 (34.1) 366 (49.4) 462 (62.3) 476 (64.3) <0.001
Smoking 253 (34.1) 202 (27.3) 176 (23.7) 208 (28.1) 0.001
Family history of premature CVD 49 (6.6) 58 (7.8) 70 (4.9) 61 (8.2) 0.223
Incident** CHD (95% CIs) 5.3(3.8-7.6) 8.6(6.5-11.5) 11.2(8.7-14.4) 15.0(12.1-18.6) <0.001
Incident** CVD (95% CIs) 6.9(5.1-9.4) 10.1(7.8-13.2) 13.2(10.4-16.6) 17.0(13.8-20.8) <0.001
Mortality** rate (95% CIs) 8.3(6.3-11.0) 7.6(5.7-10.2) 6.1(4.4-8.4) 5.8(4.2-8.1) 0.134
  1. BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL, high density lipoprotein cholesterol; MAP, mean arterial pressure 2h-PCPG, 2-hour post-challenge plasma glucose; SBP, systolic blood pressure;.
  2. Continuous variables are represented as mean (standard deviation) except for triglycerides and lipid accumulation products that are represented as geometric mean (standard deviation of geometric mean). Categorical variables are represented as frequency (percent). Confidence intervals have been provided for incident rates.
  3. **Per 1000 person per year
  4. † P-values were calculated using general linear models, for continuous variables and Cox proportional hazards regression models for incidence rates. Models were sex-specific and age-adjusted.