| Q1 (cm.mmol.l-1) <2752 | Q2 (cm.mmol.l-1) 2755-5040 | Q3 (cm.mmol.l-1) 5043-8265 | Q4 (cm.mmol.l-1) 8268-54948 | P for trends†|
---|---|---|---|---|---|
Number of participants* | 947 | 954 | 939 | 947 | Â |
Age (years) | 40.6(10.4) | 46.5(11.7) | 49.9(11.6) | 52.1(10.8) | Â |
SBP (mmHg) | 112.7(15.7) | 120.9(18.7) | 127.7(21.8) | 133.2(21.9) | <0.001 |
DBP (mmHg) | 74.6(9.4) | 78.3(10.1) | 82.0(10.7) | 84.3(10.8) | <0.001 |
MAP (mmHg) | 87.3(10.5) | 92.5(11.8) | 97.2(13.1) | 100.6(13.2) | <0.001 |
Pulse pressure (mmHg) | 38.1(11.8) | 42.5(14.5) | 45.7(16.8) | 48.9(16.8) | <0.001 |
Pulse (beat per minute) | 80.9(11.9) | 81.0(12.1) | 80.8(11.9) | 81.7(12.0) | <0.012 |
BMI (kg.m-2) | 24.7(3.5) | 27.9(3.6) | 29.9(4.2) | 31.7(4.5) | <0.001 |
Waist-to-hip ratio (%) | 78.5(6.5) | 85.3(6.6) | 88.5(6.8) | 92.2(7.0) | <0.001 |
Waist-to-height ratio (%) | 49.9(5.2) | 57.1(5.4) | 61.3(5.9) | 65.4(6.2) | <0.001 |
Lipid accumulation product | 17.8(1.6) | 42.9(1.2 | 73.0(1.2) | 135.6(1.4) | <0.001 |
Triglycerides (mmol.l-1) | 1.0(1.4) | 1.4(1.3) | 2.0(1.3) | 3.2(1.4) | <0.001 |
Total cholesterol (mmol.l-1) | 5.0(1.0) | 5.5(1.0) | 6.0(1.1) | 6.5(1.3) | <0.001 |
Non-HDL-C (mmol.l-1) | 3.8(0.9) | 4.3(1.0) | 4.9(1.1) | 5.5(1.3) | <0.001 |
HDL-C (mmol.l-1) | 1.3(0.3) | 1.2(0.3) | 1.1(0.3) | 1.0(0.3) | <0.001 |
FPG (mmol.l-1) | 5.0(1.3) | 5.3(1.6) | 5.9(2.3) | 6.5(2.8) | <0.001 |
2h-PCPG (mmol.l-1) | 5.8(1.8) | 6.5(2.3) | 7.4(3.2) | 8.7(4.2) | <0.001 |
Assignment to intervention (%) | 362 (38.2) | 387 (40.6) | 363 (38.7) | 365 (38.5) | 0.657 |
Diabetes | 46 (4.9) | 104 (10.9) | 197 (21.0) | 322 (34.0) | <0.001 |
Hypertension | 288 (28.3) | 472 (42.5) | 585 (62.3) | 699 (73.8) | <0.001 |
Smoking | 44 (4.7) | 37 (3.9) | 30 (3.2) | 28 (3.0) | 0.748 |
Family history of premature CVD | 92 (9.7) | 107 (11.2) | 129 (13.7) | 131 (13.8) | <0.010 |
Incident** CHD (95% CIs) | 1.1 (0.6-2.2) | 3.6 (2.4-5.2) | 7.4 (5.7-9.7) | 11.2 (8.9-14.0) | <0.001 |
Incident** CVD (95% CIs) | 1.3 (0.7-2.4) | 4.1 (2.9-5.8) | 8.3 (6.4-10.7) | 13.0 (10.5-16.0) | <0.001 |
Mortality** rate (95% CIs) | 2.4(1.5-3.7) | 2.5(1.6-3.9) | 4.1(2.9-5.8) | 4.5(3.3-6.3) | 0.673 |