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Figure 1 | Lipids in Health and Disease

Figure 1

From: Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family

Figure 1

DHA maintains DC immature phenotype and high endocytic capacity. CD11c+ DC (1 × 106/ml) were treated with 50 μM DHA for 24 h, followed by LPS (0.1 μg/ml) for another 24 h. (A) Cells were analyzed for MHCII, CD40, CD80 and CD86 expression by flow cytometry. One representative experiment of three is shown. (B) DC were treated as in (A) and 5 × 105 cells were incubated with FITC-dextran (0.5 mg/ml) at 4°C (negative control) or 37°C and assessed for endocytosis by flow cytometry. Results are expressed as percentage positive cells and geometric mean fluorescence (GMF) +/- SD.

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Lipids in Health and Disease

ISSN: 1476-511X