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Table 1 Characteristics of the study population at baseline and at follow up (25 weeks of treatment)

From: Effects of fenofibrate on lipid profiles, cholesterol ester transfer activity, and in-stent intimal hyperplasia in patients after elective coronary stenting

 

Baseline

Follow up

 

Control

(n = 21)

Fenofibrate

(n = 22)

P

Control

(n = 21)

Fenofibrate

(n = 22)

P

Age (years)

64 ± 8

67 ± 7

0.33

-

-

-

Male gender (%)

16 (76)

18 (82)

0.65

-

-

-

Diabetes mellitus (%)

6 (29)

6 (27)

0.92

-

-

-

Hypertension (%)

11 (52)

11 (50)

0.88

-

-

-

Current smoker (%)

5 (24)

6 (27)

0.80

-

-

-

Body mass index (kg/m2)

24.5 ± 2.5

23.7 ± 1.9

0.27

24.3 ± 2.4

23.9 ± 2.4

0.65

Total cholesterol (mg/dL)

199 ± 33

189 ± 31

0.33

180 ± 38*

171 ± 31*

0.44

Triglycerides (mg/dL)

110 ± 48

106 ± 39

0.75

102 ± 41

72 ± 37†

0.02

HDL cholesterol (mg/dL)

45 ± 11

46 ± 10

0.84

46 ± 11

50 ± 12*

0.34

LDL cholesterol (mg/dL)

110 ± 29

102 ± 24

0.32

96 ± 33*

88 ± 27*

0.40

HbA1c (%)

hs-CRP (mg/L)

6.1 ± 1.4

1.33 ± 1.26

6.3 ± 1.6

1.93 ± 2.03

0.54

0.41

6.0 ± 1.3

1.63 ± 2.19

6.2 ± 1.7

1.75 ± 3.56

0.66

0.93

CET activity (pmol/μL/h)

88.4 ± 40.7

82.6 ± 50.4

0.68

94.4 ± 59.4

57.4 ± 35.1*

0.02

  1. Data are presented as the mean ± SD. LDL = Low-density lipoprotein, HDL = High-density lipoprotein, hs-CRP = high sensitivity C-reactive protein, CET = cholesterol ester transfer. Statistical differences between the control group and the fenofibrate group were analyzed by unpaired Student's t-test. Statistical differences between values at baseline and at follow up were analyzed by paired Student's t-test. * P < 0.05 and † P < 0.01 Baseline vs. Follow up.
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Lipids in Health and Disease

ISSN: 1476-511X