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Table 1 Effects of orally administered Kurozu concentrated liquid (KCL) on morphometric and metabolic variables

From: Effects of Kurozu concentrated liquid on adipocyte size in rats

 

Control (mean ± SE)*

KCL (mean ± SE)*

Acetic acid (mean ± SE)*

Food consumption (g/day)

21.0 ±0.4

21.2 ± 0.6

21.2 ± 0.6

Body weight gain (g)

237 ± 7

243 ± 9

240 ± 9

Liver mass (g/100 g body weight)

4.55 ± 0.14

4.60 ± 0.17

4.42 ± 0.16

Leg muscle (g/100 g body weight)†

1.13 ± 0.09

1.20 ± 0.07

1.20 ± 0.07

Fat mass (g/100 g body weight)

   

   Subcutaneous

4.01 ± 0.23

3.41 ± 0.20

3.57 ± 0.21

   Mesenteric

1.16 ± 0.06

1.11 ± 0.07

1.23 ± 0.07

   Perirenal

0.453 ± 0.032

0.416 ± 0.034

0.499 ± 0.056

   Retroperitoneal

1.79 ± 0.11

1.82 ± 0.12

1.72 ± 0.09

   Epididymal

1.45 ± 0.15

1.53 ± 0.16

1.50 ± 0.13

   Brown adipose tissue

0.145 ± 0.010

0.132 ± 0.013

0.140 ± 0.009

Total mass

9.02 ± 0.32

8.42 ± 0.33

8.65 ± 0.38

Adipocyte size (μm2)

   

   Subcutaneous

2895 ± 247b

1856 ± 269a

4392 ± 492c

   Perirenal

3869 ± 324b

2547 ± 330a

3657 ± 255b

   Mesenteric

1468 ± 133a, b

1271 ± 96a

1805 ± 137b

DNA (μg/g Subcutaneous fat)

16.4 ± 2.5e

32.0 ± 4.4d

14.3 ± 2.1e

Serum

   

   Triacylglycerol (mg/dl)

253 ± 33

249 ± 32

185 ± 27

   Total cholesterol (mg/dl)

83.3 ± 9.9

68.5 ± 8.8

74.1 ± 7.4

   HDL cholesterol (mg/dl)

48.4 ± 4.7

45.6 ± 5.3

47.8 ± 2.7

   Glucose (mg/dl)

140 ± 2

138 ± 4

144 ± 2

   Adiponectin (μg/ml)

3.90 ± 0.19

4.48 ± 0.27

4.50 ± 0.37

Blood glucose AUC (mg/dl•h)

99.8 ± 6.0

104 ± 7

107 ± 13

Liver (mg/g)

   

   Triacylglycerol

24.7 ± 2.6

30.3 ± 5.6

23.5 ± 4.2

   Phospholipids

27.8 ± 0.6

25.9 ± 1.4

28.9 ± 0.6

   Cholesterol

3.53 ± 0.19

3.11 ± 0.31

3.18 ± 0.42

Fecal mass (g/day)

1.70 ± 0.05g

1.88 ± 0.03f

1.73 ± 0.05g

Fatty acid in feces (mg/day)

86.9 ± 6.4g

128 ± 7f

89.1 ± 7.6g

Fatty acid excretion rate (%/day)

3.91 ± 0.27g

5.67 ± 0.34f

3.96 ± 0.41g

  1. * Means and standard errors (SE) were determined for 7 rats per group. Different superscript letters indicate significant differences at a,b,cP < 0.05, f,gP < 0.01, d,eP < 0.001.
  2. † Leg muscle mass indicates the sum of quadriceps weight of the right and left legs.
  3. HDL = high-density lipoprotein; AUC = area under the plasma concentration time curve.
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Lipids in Health and Disease

ISSN: 1476-511X