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Table 4 Evolution of blood markers of glucid and lipid metabolisms, pro-inflammatory factors and adipokines during cure and follow-up.

From: Blood lipids and adipokines concentrations during a 6-month nutritional and physical activity intervention for metabolic syndrome treatment

  D0 D20 M3 M6 p-value
Glucidic parameters :      
   Insulinemia (microU/ml) 20,96 ± 24,13 5,73 ± 0,53 5,86 ± 0,68 6,15 ± 0,51 D0 vs D20, M3, M6 : p < 0,01
D20 vs M6 : p = 0,028
   Glycaemia (mmol/l) 6,15 ± 1,86 6,26 ± 1,76 5,7 ± 1,97 6,28 ± 2,34 D20 vs M3 : p = 0,0409
M3 vs M6 : p = 0,0121
   HOMA-IR 6,71 ± 8,86 1,62 ± 0,62 1,48 ± 0,52 1,73 ± 0,75 D0 vs D20, M3, M6 : p < 0,01
Other lipidic parameters :      
   Total cholesterol (mmol/l) 6,08 ± 1,46 5,07 ± 0,95 5,13 ± 1,25 5,56 ± 0,89 D0 vs D20, M3 : p = 0,001
   LDL (mmol/l) 3,79 ± 1,21 3,05 ± 0,87 3,47 ± 1,25 3,43 ± 0,95 D0 vs D20 : p = 0,003
   Cholesterol total/HDL 4,65 ± 2,18 3,51 ± 0,85 4,10 ± 1,24 3,83 ± 1,37 D0 vs D20. M6 : p = 0,011
   LDL/HDL 2,89 ± 1,31 2,15 ± 0,75 2,82 ± 1,21 2,42 ± 1,11 D0 vs D20, M6 : p = 0,001
D20 vs M3 : p = 0,001
M3 vs M6 : p = 0,001
Pro-inflammatory factors :      
   CRP (mg/l) 3,92 ± 2,40 3,83 ± 3,78 3,04 ± 3,23 2,45 ± 1,62 D0 vs M6 : p = 0,0303
   α1GPA (g/l) 0,84 ± 0,16 0,79 ± 0,20 0,75 ± 0,15 0,81 ± 0,16 NS (p = 0,18)
Pro-inflammatory cytokines :     
   IL1 (picog/ml) 2,96 ± 0,15 2,95 ± 0,16 2,87 ± 0,04 2,93 ± 0,12 NS (p = 0,33)
   IL6 (picog/ml) 1,17 ± 0,34 2,95 ± 0,16 2,87 ± 0,04 2,93 ± 0,12 NS (p = 0,36)
   TNFα (picog/ml) 11,06 ± 0,42 10,99 ± 0,67 10,78 ± 0,70 10,75 ± 0,51 D0 vs M6 : p = 0,0355
Adipokines :      
   Leptin (nanog/ml) 14,34 ± 7,73 9,57 ± 6,27 9,78 ± 8,59 11,00 ± 10,34 NS (p = 0,1)
   Adiponectin (μg/ml) 12,98 ± 4,82 15,56 ± 2,28 14,75 ± 4,80 15,45 ± 3,87 NS (p = 0,13)