Table 3 HOMA and FABP4 plasma levels in variant and wild allele of SNPs in obese and non-obese children.
SNPs | OB (n = 182) | p value | NOB (n = 127) | p value | ||
|---|---|---|---|---|---|---|
rs1054135 G/A | A+ (n = 121) | A- (n = 61) | Â | A+ (n = 35) | A- (n = 92) | Â |
FABP4 levels | 22.5 ± 5.5 | 16.1 ± 2.4 | <0.001 | 12.5 ± 3.5 | 7.7 ± 2.3 | <0.001 |
HOMA | 2.5 ± 0.7 | 2.6 ± 0.5 | >0.05 | 1.5 ± 0.4 | 1.3 ± 0.4 | >0.05 |
rs1051231 A/C | C+ (n = 0) | C- (n = 186) | Â | C+ (n = 0) | C- (n = 123) | Â |
FABP4 levels | N/A | 19.2 ± 4.3 | N/A | N/A | 9.1 ± 3.4 | N/A |
rs2303519 C/T | T+ (n = 66) | T- (n = 116) | Â | T+ (n = 27) | T- (n = 100) | Â |
FABP4 levels | 19.7 ± 5.4 | 19.7 ± 5.3 | >0.05 | 11.3 ± 3.2 | 10.2 ± 3.1 | >0.05 |
HOMA | 2.5 ± 1.0 | 2.6 ± 0.5 | >0.05 | 1.4 ± 0.4 | 1.4 ± 0.4 | >0.05 |
rs16909233 G/A | A+ (n = 53) | A- (n = 129) | Â | A+ (n = 28) | A- (n = 99) | Â |
FABP4 levels | 19.2 ± 5.6 | 19.2 ± 5.2 | >0.05 | 11.0 ± 2.7 | 10.8 ± 3.3 | >0.05 |
HOMA | 3.1 ± 1.1 | 2.2 ± 0.9 | <0.001 | 1.5 ± 0.4 | 1.4 ± 0.4 | >0.05 |