Cardiac and plasma lipid profiles in response to acute hypoxia in neonatal and young adult rats

Table 1 Baseline lipid class concentrations (nmol/g) in the heart and plasma of PD2 and PD60 rats - effects of age.

Lipid Class	Source	PD2	PD60	P Value
Cholesterol Ester (CE)	Heart	337.75 ± 96.09	424.50 ± 102.75	0.560
	Plasma	1249.00 ± 41.23	1449.00 ± 48.61*	0.020
Diacylglycerol (DAG)	Heart	293.75 ± 30.56	334.00 ± 13.10	0.272
	Plasma	65.75 ± 8.84	30.00 ± 7.22*	0.020
Free Fatty Acid (FFA)	Heart	1230.00 ± 113.48	2093.50 ± 153.14*	0.004
	Plasma	689.25 ± 53.22	653.00 ± 27.42	0.567
Lysophosphatidylcholine (LPC)	Heart	423.75 ± 35.01	487.00 ± 36.79	0.259
	Plasma	394.25 ± 13.92	393.00 ± 34.47	0.974
Phosphatidylcholine (PC)	Heart	8091.75 ± 759.67	14169.25 ± 789.30*	0.001
	Plasma	1246.25 ± 35.92	1130.50 ± 21.52*	0.033
Phosphatidylethanolamine (PE)	Heart	6896.00 ± 624.50	12343.00 ± 434.87*	<0.001
	Plasma	324.00 ± 23.01	181.75 ± 24.55*	0.006
Phosphatidylserine (PS)	Heart	1321.33 ± 159.17	1614.75 ± 62.90	0.112
	Plasma	n/a	n/a
Triacylglycerol (TAG)	Heart	1038.00 ± 147.45	999.25 ± 360.61	0.924
	Plasma	1527.50 ± 108.83	331.50 ± 39.01*	<0.001
Free Cholesterol (FC)	Heart	3762.25 ± 327.30	3651.00 ± 151.38	0.768
	Plasma	632.75 ± 30.51	622.25 ± 22.22	0.790

Data are presented as mean ± SEM. * Significantly different from PD2 rats. N = 4 samples for each experimental group. Note: plasma from 2-3 pups was pooled to generate one sample. N/A = not applicable.

ISSN: 1476-511X