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Table 3 Prediction of IFG and IGT by LAP, BMI, WHpR, and WHtR.

From: Diabetes prediction, lipid accumulation product, and adiposity measures; 6-year follow-up: Tehran lipid and glucose study

 

IFG

IGT

 

OR (95%CIs)§

AROC†

OR (95%CIs)§

AROC†

Men

    

20-49

    

   BMI

1.6 (1.3-2.0)

0.68

1.6 (1.3-2.1)*

0.69

   WHpR

2.2 (1.7-2.9)

0.73

3.1 (2.2-4.2)

0.74

   WHtR

2.0 (1.6-2.5)

0.72

2.3 (1.8-3.0)

0.73

   LAP

2.0 (1.7-2.5)

0.73

2.3 (1.8-3.0)

0.75

   P for trend

-

<0.001

-

<0.001

≥ 50

    

   BMI

1.4 (1.2-1.7)

0.65

1.5 (1.2-1.8)

0.61

   WHpR

1.6 (1.3-2.0)

0.66

1.7 (1.4-2.2)

0.61

   WHtR

1.6 (1.3-2.0)

0.65

1.6 (1.3-1.9)

0.61

   LAP

1.4 (1.2-1.7)

0.70

2.2 (1.8-2.8)

0.66

   P for trend

-

<0.001

-

<0.001

Women

    

20-49

    

   BMI

1.4 (1.3-1.6)*

0.76

1.7 (1.4-2.0)*

0.75

   WHpR

1.7 (1.4-1.9)*

0.78

2.3 (1.9-2.9)*

0.78

   WHtR

1.7 (1.5-1.9)

0.79

2.3 (1.9-2.7)*

0.79

   LAP

2.0 (1.7-2.3)

0.81

3.2 (2.6-4.1)

0.81

   P for trend

-

<0.001

-

<0.001

≥ 50

    

   BMI

1.1 (1.0-1.3)

0.64

1.3 (1.1-1.5)*

0.64

   WHpR

1.1 (0.9-1.3)*

0.68

1.6 (1.4-2.0)*

0.66

   WHtR

1.2 (1.1-1.5)

0.67

1.7 (1.4-2.0)

0.66

   LAP

1.5 (1.2-1.9)

0.71

2.6 (2.1-3.4)

0.71

   P for trend

-

<0.001

-

<0.001

  1. AROC, area under the receiver operating characteristic curve, BMI, body mass index; DM, diabetes mellitus; IFG, impaired fasting plasma glucose; IGT, impaired glucose tolerance; LAP, lipid accumulation product; OR, odds ratio; WHpR, waist to hip ratio; WHtR, waist to height ratio.
  2. §The odds ratios (unadjusted) of incident and prevalent DM, IFG, and IGT were estimated using logistic regression analysis corresponding to a 1 standard deviation (log-scale) unit increment in the baseline LAP, BMI, WHpR, and WHtR.
  3. *Paired homogeneity tests showed significant difference (P < 0.05). For paired homogeneity test LAP and one of anthropometric measures were fitted simultaneously in the same age- and sex-specific logistic regression model with adjustment for family history of diabetes and mean arterial pressure.
  4. † The AROCs were computed for the sex- and age-specific models adjusted for mean arterial blood pressure and family history of diabetes.
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Lipids in Health and Disease

ISSN: 1476-511X