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Table 4 Prediction of incident and prevalent DM by LAP, BMI, WHpR, and WHtR.

From: Diabetes prediction, lipid accumulation product, and adiposity measures; 6-year follow-up: Tehran lipid and glucose study

  Prevalent DM Incident DM
  OR (95%CIs)§ AROC† OR (95%CIs)§ AROC†
Men     
20-49     
   BMI 1.3 (1.1-1.5) * 0.70 1.3 (0.9-1.8)* 0.66
   WHpR 1.7 (1.4-2.1) 0.74 1.7 (1.0-2.7) 0.67
   WHtR 1.5 (1.3-1.8) 0.74 1.4 (1.0-2.1) 0.66
   LAP 1.4 (1.2-1.6) 0.75 1.7 (1.2-2.5) 0.71
   P for trend - 0.157 - 0.051
≥ 50     
   BMI 1.6 (1.3-1.9) * 0.76 1.5 (1.0-2.2) 0.69
   WHpR 1.6 (1.3-1.9) * 0.78 1.5 (0.9-2.4) 0.70
   WHtR 1.6 (1.3-1.9) * 0.79 1.5 (1.0-2.3) 0.69
   LAP 1.5 (1.3-1.8) 0.81 1.7 (1.1-2.6) 0.71
   P for trend - 0.005 - 0.492
Women     
20-49     
   BMI 1.6 (1.5-1.9)* 0.76 1.9 (1.5-2.4) 0.76
   WHpR 1.8 (1.6-2.1)* 0.78 2.2 (1.7-2.9) 0.77
   WHtR 1.9 (1.3-2.1)* 0.79 2.3 (1.8-3.0) 0.79
   LAP 2.1 (1.8-2.5) 0.81 2.6 (1.9-3.6) 0.78
   P for trend - <0.001 - 0.012
≥ 50     
   BMI 1.3 (1.1-1.4)* 0.65 1.5 (1.1-2.1) 0.63
   WHpR 1.1 (1.0-1.3)* 0.68 1.6 (1.1-2.3) 0.64
   WHtR 1.3 (1.1-1.5)* 0.68 1.9 (1.3-2.8) 0.65
   LAP 1.5 (1.3-1.8) 0.72 2.1 (1.3-3.3) 0.65
   P for trend - <0.001 - 0.567
  1. AROC, area under the receiver operating characteristic curve, BMI, body mass index; DM, diabetes mellitus; IFG, impaired fasting plasma glucose; IGT, impaired glucose tolerance; LAP, lipid accumulation product; OR, odds ratio; WHpR, waist to hip ratio; WHtR, waist to height ratio.
  2. §The odds ratios (unadjusted) of incident and prevalent DM, IFG, and IGT were estimated using logistic regression analysis corresponding to a 1 standard deviation (log-scale) unit increment in the baseline LAP, BMI, WHpR, and WHtR.
  3. *Paired homogeneity tests showed significant difference (P < 0.05). For paired homogeneity test LAP and one of anthropometric measures were fitted simultaneously in the same age- and sex-specific logistic regression model with adjustment for family history of diabetes and mean arterial pressure.
  4. † The AROCs were computed for the sex- and age-specific models adjusted for mean arterial blood pressure and family history of diabetes.