Figure 6

Brefeldin A inhibits basal apoE secretion but not the apoA-I induced apoE secretion in mature human adipocytes. Mature adipocytes were pre-treated with BFA (5 μg/ml) for 12 hours and apoE secretion was measured in the medium of matures adipocytes cultures treated or not with apoA-I (10 μg/ml) at 6 hours by ELISA. The graph represents the mean ± SD of the results from 4 patients (n = 6 for each condition, for each patient). all raw data has been normalised versus control.***P < 0.001% versus control cells, ###P < 0.001% versus apoA-I cells.