Table 3 Distribution of the genotypes, alleles frequencies and odd ratio of the β2 Gln27Glu polymorphism in overweight and control subjects.
Genotype | Sex | Control M:35 F: 80 T = 115 | Overweight M:28 F: 40 T = 68 | Obese M:46 F: 100 T = 146 | χ2 Odds ratio(95% CI) | P- value |
|---|---|---|---|---|---|---|
Genotype Frequency | ||||||
Gln\Gln | M | 24 (68.57) | 17 (60.7) | 27 (58.67) | χ2 M= 1.19 F= 2.23 | P value M = 0.880 |
F | 51 (63.75) | 26 (65) | 60 (60) | |||
T | 75(65.2) | 43(63.2) | 87(59.6) | |||
Gln\Glu | M | 5 (14.28) | 5 (17.58) | 7 (15.21) | Odds ratio (95% CI) Control vs OW 1.1 (0.5, 2.39) | F = 0.693 |
F | 13 (16.25) | 6 (15) | 12 (12) | |||
T | 18(15.7) | 11(16.2) | 19(13.0) | |||
Glu\Glu | M | 6 (17.12) | 6 (21.42) | 12 (26) | Odds ratio (95% CI) Control vs Obese 1.567(0.85,2.87) | P value for Odds ratio in normal vs overweight and normal vs obese: P > 0.05 |
F | 16 (20) | 8 (20) | 28 (28) | |||
T | 22(19.1) | 14(20.6) | 40(27.4) | |||
Allele Frequency | ||||||
Allele Gln27 | T | 73.0% | 71.3% | 66.1% | Odds ratio (95% CI) Control vs OW 0.95 (0.71, 1.27) | P = 0.70 |
Allele Glu27 | T | 27.0% | 28.7% | 33.9% | Odds ratio (95% CI) Control vs Obese 0.87 (0.74, 1.2) | P = 0.09 |