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Table 8 Effect of FVBM, F18 bioactive compound and atorvastatin on the ratios of plasma HDL-C/TC, HDL-C/LDL-C, TC/HDL-C and LDL-C/HDL-C in Triton WR-1339 induced hyperlipidemic rats after 18 hours of the treatment

From: Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait

Group/Ratio†

HDL-C/TC

HDL-C/LDL-C

TC/HDL-C

LDL-C/ HDL-C

NC

0.3625 ± .025*

0.7746 ± 0.088

2.758 ± 0.105

1.2909 ± 0.0576

HLC

0.0615 ± 0.003*

0.0795 ± 0.0074

16.244 ± 0.76

12.5727 ± 0.65

(−5.89 f)a

(−9.74 f)a

(+5.88 f)a

(+9.73 f)a

FVT-1

0.2110 ± 0.0048*

0.3281 ± 0.0075

4.737 ± 0.094

3.0473 ± 0.086

(+4.13 f)a

(−3.43 f)a

(−4.12 f)a

(+3.43 f)a

FVT-2

0.3525 ± 0.0071*

0.7518 ± 0.074

2.836 ± 0.115

1.3299 ± 0.034

(+9.45 f)a

(−5.72 f)a

(−9.45 f)a

(+5.73 f)a

CT

0.3337 ± 0.0042*

0.6518 ± 0.015

2.996 ± 0.081

1.5340 ± 0.0691

(+8.19 f)a

(−5.42 f)a

(−8.21 f)a

(+5.42 f)a

AT

0.3630 ± 0.0036*

0.7497 ± 0.028

2.754 ± 0.129

1.3338 ± 0.064

(+9.43 f)a

(−5.89 f)a

(−9.42 f)a

(+5.90 f)a

  1. †For the calculation of ratios, data is taken from Tables 5 and 6.
  2. *Values are mean (mg/dl) ± SD from plasma of 5 rats in each group.
  3. NC, normal control; HLC, triton induced hyperlipidemic control; FVT-1, fed 50 mg FVBM extract/rat; FVT-2, fed 100 mg FVBM extract/rat; CT, fed 1 mg F18 bioactive compound/rat and AT, given 1 mg atorvastatin/rat once.
  4. ‘f’ stands for fold.
  5. Significantly different from NC at ap < 0.001.
  6. Significantly different from HLC at ap < 0.001.