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Table 1 The protocol and stress procedures for chronic mild stress

From: Reduced cholesterol is associated with the depressive-like behavior in rats through modulation of the brain 5-HT1A receptor

Date Stressor
Monday Cold immobilization for 1 h at 4°C, tilted cages 45° for 24 h
Tuesday Immobilization for 1 h, crowding for 24 h
Wednesday Forced cold swim for 5 min, soiled bedding for 24 h
Thursday Immobilization for 1 h, vibration for 1 h
Friday Tilted cages 45° for 24 h, cold immobilization for 1 h at 4°C
Saturday Forced cold swim for 5 min at 4°C, crowding for 24 h
Sunday Vibration for 1 h, soiled bedding for 24 h